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'user defined automatic repeat'

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Clinical Chemistry

ADVIA 2400 Chemistry System The right balance of speed and efficiency The ADVIA® 2400 Clinical Chemistry System manages the most demanding workloads and meets high turnaround-time (TAT) goals. Its menu includes methods for testing drugs-of-abuse, therapeutic drugs (TDM) and new assays such as cystatin C and CardioPhase® hsCRP. The ADVIA 2400 Clinical Chemistry System offers: High throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage heavy workloads Rapid, consistent, 2-second cycle time for faster tube speed and test throughput User-defined automatic repeat, dilution, and reflex testing Large onboard reagent capacity and optional concentrated reagents help to minimize intervention demands Refrigerated onboard storage of controls and reagents for extended stability and increased productivity Automation-ready design: no additional hardware required Features & Benefits The ADVIA 2400 Clinical Chemistry System meets today’s high turnaround-time goals with a throughput of up to 2400 tests/hour. In addition to assays for general and specialty chemistries, its menu includes assays for specific protein measurement, drugs-of-abuse testing (DAT), and therapeutic drug monitoring (TDM). Interesting new assays such as cystatin C, HbA1c with automated sample pretreatment, and CardioPhase® hsCRP can now be included in your routine testing. The ADVIA 2400 Chemistry System pushes productivity levels while maintaining the reliability and stability that keep laboratories up and running. A rapid, 2-second probe cycle time maximizes tube speed and test throughput and combines with the system’s efficient automation-readiness to provide the turnaround time needed for high-volume laboratories Superior Speed and Productivity Throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage the heaviest workloads Rapid, consistent, 2-second cycle time Throughput of 200 tubes per hour, even when running three ISE tests and nine photometric tests per sample Automatic Sample Retain technology, auto-repeat, auto-dilution, and auto-reflex testing Automation-ready Point-in-space aspiration enables connectivity to a track. Redundant sample loading provides built-in backup and easy handling of non-routine samples. Direct sampling from track prevents tubes being detained at an analyzer and reduces aliquoting. Minimal Need for Operator Intervention Minimal-maintenance ISEs Large onboard reagent capacity and optional concentrated reagents for fewer interruptions No-maintenance, 37°C incubation oil bath Auto-calibration and auto-QC from refrigerated onboard calibrators and controls Microvolume technology with 32,000 tests onboard and up to 60 days' onboard stability for improved walkaway time. Concentrated reagents for increased maximum capacity. Remote diagnostics and Inter-Laboratory Quality Control (ILQC) options Exceptional Reliability Sample integrity check for icterus, hemolysis, and lipemia Sample probe with automatic clot/clog detection, liquid-level sensing, short-sample detection, and crash protection Advances in onboard reagent stability, calibration frequency, reduction in interferences, and expanded assay linearity

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Hematology

At Mindray, we pride ourselves on our dedication and experience in developing better solutions for small labs. Our new 3-part hematology analyzer is the culmination of that effort. It provides small labs with more confidence in results and less turnaround time. Features CBC+3-DIFF, 21 parameters+3 Histograms Throughput: up to 60 samples per hour 10.4 inch TFT touch screen Only three reagents needed Open vial sampling Large storage capacity: up to 400,000 samples Original QC, calibrators and reagents Product Specification Automation Fully Automatic Instrument Name Hematology Analyzer Brand Mindray Usage/Application Clinical Differential Type 3-Part Number Of Chambers 2 Number Of Parameters LYM Model Name/Number BC-30s User Input Touch Voltage 240 V Frequency 50 Hz Power Source Electric

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Hematology

n large laboratories, rows of instruments are seen working tirelessly like miniature factories – only they produce not commodities but medical test results. Mindray CAL 8000 new-generation cellular automation line is one of them, but unlike a typical workhorse, it is intelligent. It is a highly automated workstation for smarter, faster, and more accurate cellular analysis. It can perform competently in the face of these challenges. The workstation can hold up to four units of BC-6800 automated hematology analyzer, which utilizes the advanced SF Cube technology and 3-D scatter grams to help doctors better differentiate blood cell populations and reveal abnormal cells undetectable by conventional techniques. With 125 CBC tests per hour per unit, BC-6800 brings the process rate of the workstation to 20–30 percent higher than other similar models, effectively alleviating laboratory's stress during the peak processing hours. On CAL 8000, the hematology analyzer, slide maker and stainer, CRP analyzer, and HbA1c analyzer are all integrated into one seamless production line through automated track modules and trolley. Simply by loading a single tube of blood sample onto the automation system, one can get all the test results. This innovative walk-away automation functionality has made possible the CBC+CRP+HbA1c testing all in one streamlined workstation for the first time in the industry. It offers a smart solution, or rather, a smart expert – the labX pert 2.0. It is a software that can automatically sort out the suspected samples for manual validation. The pathologist then decides if rerun or microscopic review is warranted based on their clinical experience. It avoids wasting slides and reduces extra work. Moreover, the onboard automated re-exam functionality also helps enhance work efficiency. The CMU software The touch screen is the “brain” of CAL 8000. It optimizes the distribution of workload between each analyzer unit and decides which sample requires a blood smear. It displays the status of each analyzer or SC-120 installed on CAL 8000 as well as the volume of balance reagent. This intuitive software can tell the users all necessary information of CAL 8000 at any given time. Consequently, the users spend less time operating CAL 8000 and can arrange their working schedule better. Multi “R” tests The CAL 8000 can automatically distribute the samples with “Repeat”, “Rerun” and “Reflex” criteria which are pre-defined by users.The re-exam criteria on CAL 8000 can be defined by many conditions, such as time, patient’s age, gender, department, etc. This helps minimize the number of blood smears. Special tube racks The special tube racks utilize different barcodes to differentiate specific testing purposes, such as “QC”, “Slide making & staining only” and “RET test only”. The special tube racks can carry the tubes to perform these specific functions in the simplest way.

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Clinical Chemistry

Best Semi Automatic Biochemistry Analyzer AT Smart from Accurex. AT SMART is a Biochemistry/Clinical Analyzer with a user-friendly and the human interface is via touch screen. It measures the optical densities of samples & calculates the sample concentration which are used for biochemical investigation. This Biochemistry Machine operates from near UV to visible range. Semi Auto Analyzer AT SMART is CE certified and has undergone rigors testing before being delivered to customers. About •SMART MAINTENANCE •SMART LIS •SMART INVENTORY MANAGEMENT REDUCED ERRORS: IT allows for the accurate collection of data, automated workflows & minimized waste. SAVES TIME: Patient monitoring can be done in real-time, saves engineers visiting time. BETTER PATIENT EXPERIENCE: A connected laboratory system creates an environment that meets each patient’s needs. INSTRUMENT BREAKDOWN MANAGEMENT: Real-time data helps to monitor instrument performance. ONLINE REACTION CURVES: • Real time reaction curve with special • Flagging gives confidence in patient reports. INTELLECTUAL SOFTWARE: • User friendly Device. • 150 Direct access test keys gives freedom to select parameters easily. • Availability of different assay modes. DRY BATH INCUBATOR: • Dry bath incubator with 12 test tube positions • Mini size with 15 minutes start up time FEATURES: •Remote access & monitoring via Internet •150 test parameters •Built-in thermal printer to print results, enzymatic curves and standard calibration curves •Large graphic display with real time graph display for enzymatic reaction •Touch screen interface with dynamic test access key SPECIFICATIONS: Methodology- • Absorbance • Endpoint with standard, factor, sample blank & diffrential • Two-point (fixed time) and multi point kinetics • Multi standard calibration • Mono or bi-chromatic reading • Turbidimetry Optical System- • Principle: photometry • Range of measurement: 0.0-3.0A • Spectral range selection: Automatic via filter wheel • Filters: 340, 405, 505, 546, 578 and 630 nm plus two free position • Bandwidth:10nm (+/- 2nm) • Light source: Life Long Halogen lamp • Blanking: Automatic • Detector: Silicon Photodiode Photometer- • Peltier regulated 25ºC, 30ºC and 37ºC • Flow cell of 18 µ L • Continuous flow system with peristaltic pump • Programmable Sipping Volume Memory- • 150+ User Defined Test Programs • 1000 test results in instrument memory and unlimited test resultresult storage via cloud • Reagent Blank • 2 Level of QC Quality Control- • Levy-Jennings chart using westgard’s rules • 30 Normal and abnormal QC values for selected test User Interface- • Graphic LCD back Lit 240×64 pixels • Touch Screen input • Data port and cloud connectivity • Type : Graphic thermal printer Power & Dimensions- • Voltage : 220 V • Frequency : 50 Hz • Maximum power : < 150 VA • Maximum relative humidity : 75% • Compact form factor • Weight: < 6kgs Safety Information Precautions • Instrument should be operated only by authorised or trained personnel • For any reasons, unauthorised personnel should not be engaged for servicing or removing the cabinet • Power source should be regulated either by voltage stabilizer or regulated power back up (UPS). If inverter is been used, please ensure there exists a voltage stabilizer • Reagents recommended by the company to be preferably used • Flow cell needs to be rinsed regularly with the company recommended flow cell cleaning solution • User is requested not to use any other pointing devices other than being supplied by company while operating touch screen • The operating environment should be clean and protected from direct sunlight • During the day at the end of the work, it should be ensured that flow cell is always filled with distilled water • During transport / longer duration of shut down, th Direction for Use Please ensure that the power source is properly grounded and voltage between Line and Ground is less than 2V AC – 5V AC. • Please ensure that the instrument is placed on a firm table, clean environment, and sufficient ventilation space. • Switch On the instrument. • Instrument will run its own internal diagnostic routines, to ensure proper working of critical functions. • Allow the instrument to stabilize for 10 minutes. • During the stabilization time, please wash the flow cell with cleaning solution and distilled water for at least two times. • During shut down, ensure that the flow cell is cleaned with flow cell cleaning solution and rinsed thoroughly using distilled water. • For overnight shutdown, please ensure flow cell is filled with distilled water. • Cover the instrument with the given dust cover Other Info GENERAL INFORMATION While installing and setting up the instrument, few safety warnings and general precautions described in the further sections must be observed. A. Power Supply : • Power source should be grounded and have either servo stabilizer or regulated power back up • Power cord should be CE , CSA and UL marked • Voltage : 115 – 230 Volts ± 10% 50 – 60 Hz • Grounding: Make sure that electrical power source is properly grounded.

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Clinical Chemistry

Product Description: XL-640 with CRS is a random access, discrete, patient prioritized, fully automated clinical chemistry analyzer with autoloader designed to meet the needs of today’s modern clinical laboratories with high workload. Once samples are loaded, it is a complete walk-away system. XL 640 CRS is designed to operate smoothly over the long haul and to deliver consistent quality report. Product Features: Throughput of 400 tests/ hour (Photometric) and 640 tests/hour with ISE 56 Reagent Positions with On-board cooling for reagents 162 Sample positions with /Autoloader Separate probes for reagent R1 & R2 and dedicated probe for sample Clot detection for sample probe, Reflex testing and Serum Indices identification 72 permanent hard glass cuvettes with On-board Laundry Automatic dilution for high abnormal samples & Auto Rerun facility Extensive QC Programmes with Levy –Jennings Curve & QC rules. Automatic calculation for Mean SD & CV% Direct loading for primary tubes Touch screen User Friendly GUI with Bi-directional connectivity. System General System Type: Automated, Discrete, Random Access, Patient Prioritized Clinical Chemistry Analyzer with Autoloader Throughput: 400 photometric tests/hour & 640 tests/hour with ISE (*optional ISE with Na, K, Cl, Li) Analytical Methods: 1-Point, 2-Point, Rate-A, Rate-B, Direct Potentiometry(optional) Barcode Reader: Both for Samples & Reagents (Optional) Reactions Tray: 72 hard glass cuvettes Reaction Mixing: Dual Stirrer with variable speed Reading Volume: 180 µl On-Board Laundry: 6 stage cleaning, 2 stage drying Photometer: Multi-wavelength diffraction grating with 12 wavelengths (340, 376, 415, 450, 480, 505, 546, 570, 600, 660, 700 & 750 nm) O.D. Range: 0 - 3.0 Light Source: Halogen Lamp Detector: Silicon Photodiodes Water Consumption: < 14 liters/hour Programmable Parameters: Default system pack parameters + upto 99 user defined parameters, Unlimited profiles and unlimited calculation items Quality Control: Q.C. plot data with Q.C. Rules. Provision for lab mean. Twin plot. Caliberation: K- factor, Linear (1,2 point and multipoint) 4P and 5P Logit-log, Cubic spline,exponential, polynomial. On-board serial dilution for calibrator Power Requirement: AC 220 V ± 10 %, 50 Hz or AC 110 V ± 10 %, 60 Hz Power Consumption: 800 VA Dimensions: Approximately 897 mm (w) x 655 mm (D) x 1170 mm (H) Weight: Approximately 200 Kg Sample Handling Sample: Serum, Plasma, Urine, CSF, Whole blood, other Sample Unit: upto 162 positions for samples/STAT/calibrator/controls with Autoloader Sample Pipetting: 2-70 µl (adjustable in 0.1 µl steps) for biochemistry,70 µl fixed for ISE capacitance probe with liquid level sensing and vertical obstruction detection , clot detection and serum indices and Reflex Testing Auto Rerun: Repeat with same, increade and decresaed volume (upto 1:150) Sample Tubes/Cups: Primary tubes of 5 ml, 7ml and 10 ml and sample cups Reagent Handling Reagent Tray: 56 positions for reagents with on-board cooling Reagent Pipetting: R1: 60 - 300 µl (Adjustable in 1 µl step) R2: 0 or 10 - 300 l (Adjustable in 1 µl step) Capacitance probe with level sensing and vertical obstruction detection System Interface Analyzer-PC: USB PC- HOST Computer: Bidirectional TCP/IP and RS - 232 PC- Printer: USB Operating System: Windows based with Touch Screen User Friendly GUI Database: Unlimited Results

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Clinical Chemistry

Product Description: Erba Chem 5X is a low cost, compact, high performance semi automated analyzer for all routine Clinical chemistry, Electrolytes, Immunoturbidimetric assays. Product Features: Semi automated analyzer Multi-point calibration with graphical display Repeat measurement with read key USB connectivity to external printer and PC Monochromatic & bichromatic measurement Built- in self diagnosis with help key facility Dual cuvette system and inbuilt thermal printer 222 open user-defined test programs 9 Assay modes 1 Point Linear 2 Point Linear 1 Point Non Linear 2 Point Non-linear Rate A Linear Rate A Non-Linear 1 Point Sample Blank Linear 1-Point Sample Blank Non-Linear Absorbance Mono & Bichromatic measurement Photometric range from 0 to 3.0 OD Photometric resolution up to 0.0001 Automatic zero setting Static Photometer: 340-630 n.m. Wavelength: 340, 405, 505, 546, 578, 630 n.m. + 2 Optional positions Multi-Point calibration with graphical display Levy-Jennings graph for quality control 5000 Test patient results storage Peristaltic pump aspiration system with calibration facility Dual cuvette system: Flow cell volume-33 µl 10 mm external glass / Polystyrene Aspiration volume from 100 to 2997 µl Temperature control at 20° to 40° in step of 1°C Repeat measurement by read key Collated report date wise, ID wise (Alphanumeric) Inbuilt Thermal Printer Direct Printer Connectivity through USB Port USB Connectivity to PC Connectivity to external Incubator (Optional with 16 position)

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Hematology

BC-6800 Today, laboratories not only need more reliable routine CBC plus 5-part diff WBC testing by way of high processing speed, but are also looking for options that extend the analyzer's output in form of Reticulocytes, Nucleated RBCs, Fluorescent Platelet counts etc. for wider clinical application and research. On the other hand, they are restricted by limited budgets. BC-6800 can help to meet all these needs just perfectly and even exceed the expectations. Additional parameters for further clinical applications IMG(#,%) parameters provide information about immature granulocyte, including promyelocytes, myelocytes and metamyelocytes. HFC*(#,%) parameters represent high fluorescent cell population, such as blasts and atypical lymphocytes. RET(#,%) extend valuable help in the differential diagnosis and/or therapeutic monitoring of anemias. IRF is parameter concerning immature reticulocytes, which can assist in early diagnosis of anemia and monitoring the bone marrow response to therapy. InR*(#,‰) are parameters regarding infected red blood cell. The red blood cells may infected by plasmodium, which can cause malaria. * means research parameters SF Cube Technology SF Cube is a pathbreaking technology for reliable blood cell analysis, including WBC differential, Reticulocytes and NRBC with efficient flagging. After reaction with proprietory reagents, the targeted blood cells undergo 3D analysis using information from scatter of laser light at two angles and fluorescence signals. The 3D scattergram builds the power to better identify and differentiate blood cell populations, especially to reveal abnormal cell population undetected by other techniques. Minimizing interference to ensure more accurate results NRBCs are counted in a dedicated channel by SF cube method, which automatically corrects total WBC count and 5-part Diff results when NRBCs are detected. The Focusing Flow-DC method minimizes the interference traditionally encountered in DC technology to produce near gaussian histograms. PLT-O result avoids the interference from microcytic and fragmented RBCs, large platelets and/or platelet clumps by fluorescent stain, and enhances the results accuracy and sensitivity. High automation to minimize the workload Throughput for 125 tests/hour, autoloader for 100 sample tubes capacity Bi-directional LIS with HL7 or ASTM communication protocol Customizable re-exam rules allow users to define their re-exam criterion according to lab’s practice

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Clinical Chemistry

The Autochem Xact Pro is a Fully Automatic Random Access Clinical Chemistry Analyzer. It is a compact, benchtop analyser with throughput up to 200 tests per hour. First-in-Class On-board Warm-water Laundry System Probe with Collision-Protection System Multi function Probe which works as mixer also Probe with Capacitance based liquid level sensor Robust Multi-functional Software Intelligent" Mixing Arm Removable & flexible Sample - Reagent Disc with 40 Open position for reagent & samples respectively. DESIGNED FOR UNINTERRUPTED WORK FLOW OTHER FEATURES ROBUST MULTI-FUNCTIONAL SOFTWARE Probe with Collision-Protection System Both horizontal and vertical collision protection ensures that system re-starts testing after any unwanted physical intervention. This prevents wastage of reagents, saves test time and increases life of probe Multi functional Probe Probe has flexibility to work even as a mixer in case in-built mixer does not work Probe with Capacitance based liquid level sensor Probe with liquid level sensor checks and indicates the presence of adequate sample or reagent in the container before starting testing process. Thus prevents unwanted interruptions in testing process “Intelligent” Mixing Arm User defined, variable three level mixing speed ensure thorough mixing Accurate performance of regular and immunoturbidimetric assays Independent cleaning station for mixer which prevents carry-over ensuring high precision Removable & flexible Sample – Reagent Disc 40 Open position for reagent & samples respectively Facility to use primary & variable sample cup as well as non fixed position for Sample, Control, Calibrator & STAT samples Two bottle sizes of 18 mL or 5 mL with unique design to reduce reagent dead volume Optional internal Reagent & Sample barcode reader makes the operation user friendly & ensure correct result reporting Reaction tray 60 reusable plastic reaction cuvettes which is also scanned before performing the test which means less recurring cost without compromising on quality. To assure precise results Individual replacement of cuvette offer lower consumable cost REFLEX Testing Functionality Allows user to program Low & High panic value for a particular test which triggers auto-testing of assigned tests which ensures faster and comprehensive reporting Dynamic & Real-time display of Test Running Status for quicker decision making Running status of reagent tray, Sample tray & reaction tray Real-time monitoring of Reaction curve On board inventory management Real-time monitoring of reagent residual volume saves reagent cost & time In-built full QC Program Provision to run 3 levels of control with Levey Jennings graph which gives confidence in reporting with multiple rules (1SD, 2SD and 3SD) Reagent, Calibrator & Control lot monitoring User friendly Bi-Directional LIS Interface

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Clinical Chemistry

Best Fully Automated Clinical Chemistry Analyzer – Sphera M from Accurex. This chemistry analyzer is made in Italy & provides Accurate, Precise and Rapid Testing Solution. Sphera M is a Compact, fully automated, open random-access analyzer. The Minimum reaction volume is 210 µl, Minimal < 1L/h water consumption, 80 reusable UV transmitting Bionex® plastic cuvettes, 8-step wash station. It has Removable refrigerated tray with 30 open reagent positions for 50 ml or 20 ml bottles. Multiple virtual reagent disks can be programmed. The Chemistry analyser also does Auto-wash of inner & exterior probe surface. QUALITY CONTROL & CALIBRATION QUALITY CONTROL: • Levey-Jennings plots and Westgard multi rules • Upto 3 QC levels per test • QC monitor and reports • Method statistics: Test counter, CV%, mean, graphical trend analysis CALIBRATION: • Method and reagent monitor (volumes, available tests, calibration, QC status) • Automatic pre-dilution for calibrators • Upto 8 calibrators per method • Auto recalculation of result using last calibration. UNIQUE SOFTWARE DESIGN AND ARCHITECTURE: • Software designed for touch screen use • Intuitive user interface • Continuous loading of samples and reagents • Random-access and STAT • Free choice of execution order • Extended walk-away capability • Results archive with cumulative charts • Programmable automatic start up routine • Multiple work lists INTERFACE: • Bi-directional LIS, ASTM, over ethernet port of the external PC • Positive identification of samples with internal barcode reader (optional) • Printing on any Windows 7®/8® compatible printer • Method defined washing programs SYSTEM PACKS FOR SPHERA™ Accurex has developed dedicated system packs for Sphera™. Our biochemistry reagents have been intensively evaluated and validated to achieve the highest performance in Sphera™. Accurex recommends the use of these system packs according to instructions and applications validated by Accurex. Safety Information 8-step wash station for thorough cleaning of each cuvette (Needles: 6 dispensing, 6 aspiration, 1 cleaning) • Two types of systemic and special washing solutions for removing obstinate probe residues Direction for Use QUALITY CONTROL • Levey-Jennings plots and Westgard multi rules • Upto 3 QC levels per test • QC monitor and reports • Method statistics: Test counter, CV%, mean, graphical trend analysis CALIBRATION • Method and reagent monitor (volumes, available tests, calibration, QC status) • Automatic pre-dilution for calibrators • Upto 8 calibrators per method • Auto recalculation of result using last calibration Other Info Accurex has developed dedicated system packs for Sphera™. Our biochemistry reagents have been intensively evaluated and validated to achieve the highest performance in Sphera™. Accurex recommends the use of these system packs according to instructions and applications validated by Accurex.

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