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Clinical Chemistry

ADVIA Chemistry XPT System An advanced, automated clinical chemistry analyzer for high-volume laboratories The ADVIA® Chemistry XPT System provides timely, reliable results with continuous operation to meet the chemistry workloads of the most demanding laboratories. Delivers high throughput of up to 2400 tests per hour. Manages comprehensive testing with a menu of more than 115 assays. Improves workflow using automation and system technologies such as micro-volume and aliquot retention. Features & Benefits The ADVIA Chemistry XPT System*** is engineered for continuous operation and timely, accurate results—supporting you to reach your full potential today and be prepared for tomorrow. With an advanced user interface that is easy to use and VeriSmart Technology to support accuracy of testing, the ADVIA Chemistry XPT System predictably and consistently delivers timely, reliable results to meet expanding workloads. Simplified, Continuous Operation Simplify operation and training with the intuitive, icon-driven user interface. Extend walkaway times with concentrated reagents that provide high test capacity onboard. Quickly load most system fluids on the fly. Automate calibration, QC, startup, and shutdown. Consistent, Predictable Turnaround Time and Accuracy Offer a comprehensive chemistry menu of over 115 assays, including general and specialty chemistry, DAT, TDM, and specific proteins. Push productivity with a throughput of up to 2400 tests per hour (1800 photometric, plus 600 ISE). Control testing: STAT and specialty samples can always be front-loaded while an automation track is running. Designed for Automation Adapt and grow with direct connectivity to Siemens Healthineers and . Simplify your laboratory operations with connectivity to IT solutions including , , and . Increase productivity and efficiency with direct-from-track sampling and onboard aliquoting that allows samples to be immediately released to the next workstation. Do More with Less Reduce blood-draw requirements with micro-volume technology that uses a single 30 μL sample for up to 15 tests. Eliminate sample callback with automated, pre-programmable dilution, reflex, and rerun testing that uses an onboard aliquot. Improve workflow and accuracy with VeriSmart echnologies that perform hardware and software checks at all stages of sample processing.

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Clinical Chemistry

Autozyme Alkaline Phosphatase 60 Diagnostic Reagent (Pack Size : 12 x 5 ml) from Accurex. Alkaline Phosphatase 60 are used in the diagnosis of hepatobiliary disorders and bone disease associated with increased osteoblastic activity. Alkaline Phosphatase high levels may be a sign of a liver problem or a bone disorder Alkaline Phosphatase 60 reagent is set for determination of Alkaline Phosphatase activity based on kinetic method using p-nitrophenyl phosphate (p-NPP), the reagent is a Highly stable reagent & its activity can be determined in just 2.5 minutes. About Autozyme Alkaline Phosphatase is a reagent set for determination of Alkaline Phosphatase activity based on kinetic method using p-nitrophenyl phosphate (p-NPP) Autozyme Alkaline Phosphatase is a single reagent system using one step procedure Autozyme Alkaline Phosphatase has one step reconstitution. It involves dissolving substrate tablet in diluent Autozyme Alkaline Phosphatase is a Highly stable reagent Autozyme Alkaline Phosphatase activity can be determined in just 2.5 minutes Pack Size : 12 x 5 ml Principle The working solution is stablə for 21 days at 2- 8°C. The working solution should be prepared and stored in the dark (working solution bottle) provided.This is critical because the reagent is light sensitive. It should therefore be kept away from direct light. Alkaline Phosphatase cleaves p-nitrophenyl phosphate (p-NPP) into p-nitrophenol and phosphate. p-nitrophenol is a yellow color compound in alkaline medium and absorbs light at 405 nm. The rate of increase in absorbance at 405 nm. is proportional to Alkaline phosphatase activity in specimen. Quality Control To ensure adequate quality control, it is recommended that each batch should include normal and abnormal commercial reference control serum. It should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect the performance of this test include proper instrument function, temperature control, cleanliness of glassware and accuracy of pipetting. Other Details The kit should be stored at 2-8°C and is stable till the expiry date indicated on the label. The working solutions of Non Prostatic Acid Phosphatase & Total Acid Phosphatases are stable for 7 days at 2-8°C.

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Clinical Chemistry

Autozyme Alkaline Phosphatase 300 Diagnostic Reagent from Accurex (Pack Size : 30 x 10 ml). Alkaline Phosphatase reagent is used for determination of Alkaline Phosphate activity based on kinetic method using p-nitrophenyl phosphate (p-NPP). Alkaline Phosphatase is a single reagent system using one step procedure & Alkaline Phosphatase activity can be determined in just 2.5 minutes & is is a Highly stable reagent. Alkaline Phosphatase cleaves p-nitrophenyl phosphate p- NPP in the presence of magnesium ions to form p nitrophenol & phosphate. About Method – p-NPP-DEA Buffer – Kinetic reaction with 60 seconds lag phase – Easy reconstitution : Tablet + Diluent – High liquid stability : 21 days Autozyme Alkaline Phosphatase is a reagent set for determination of Alkaline Phosphate activity based on kinetic method using p-nitrophenyl phosphate (p-NPP) Autozyme Alkaline Phosphatase is a single reagent system using one step procedure Autozyme Alkaline Phosphatase has one step reconstitution. It involves dissolving substrate tablet in diluent Autozyme Alkaline Phosphatase is a Highly stable reagent Autozyme Alkaline Phosphatase activity can be determined in just 2.5 minutes Principle Alkaline Phosphatase cleaves p-nitrophenyl phosphate p- NPP) in the presence of magnesium ions to form p nitrophenol and phosphate. The intensity of the yellow color formed is directly proportional to the Application alkaline phosphatase activity in the specimen and measured kinetically. Quality Control To ensure adequate quality control, it is recommended that each batch should include normal and an abnormal commercial reference control serum. It should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect the performance of this test include proper instrument function, temperature control, cleanliness of glassware and accuracy of pipetting. Other Details Two liquid reagent systems. Stable till the expiry date indicated on the label when stored in 2-8°C.

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Clinical Chemistry

utozyme Albumin 300 Diagnostic Reagent from Accurex. Albumin 300 is used for determination of albumin in serum or plasma based on BCG method. Autozyme Albumin is a single reagent system which is ready to use, Albumin is linear up to 6 gm% & can be determined in 1 minute at room temperature. Serum albumin in the presence of Bromocresol-green under acidic condition forms a green coloured complex. Albumin normal range is 3.4 to 5.4 g/dL (34 to 54 g/L). About Autozyme Albumin is a reagent set for determination of albumin in serum or plasma based on BCG method Autozyme Albumin is a single reagent system, ready to use. Autozyme Albumin is linear up to 6 gm% Albumin can be determined in 1 minute at room temperature The shelf-life of Autozyme Albumin is 18 months Pack Size : 2 x 50 ml Principle Serum albumin in the presence of Bromocresol-green under acidic condition forms a green coloured complex, The absorbance of this complex is proportional to the albumin concentration in serum or plasma. Quality Control To ensure adequate quality control, it is recommended that each batch should include a normal and an abnormal commercial reference control serum,. it should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect the performance of this test include proper instrument function, cleanliness of glassware and accuracy of pipetting. Other Details The reagents are for in vitro diagnostic use. BCG reagent and standard should be stored at temperature indicated on the bottle label.

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Clinical Chemistry

Autozyme Albumin 100 Diagnostic Reagent (Pack Size : 2 x 50 ml) from Accurex. Albumin reagent is used for determination of albumin in serum or plasma based on BCG method, can be determined in 1 minute at room temperature. BCG reagent and standard should be stored at temperature indicated on the bottle label. Accurex has gained considerable expertise in manufacturing & marketing of In-vitro Diagnostic reagents. Serum albumin in the presence of Bromocresol-green under acidic condition forms a green colored complex. Albumin normal range is 3.4 to 5.4 g/dL (34 to 54 g/L). About Autozyme Albumin is a reagent set for determination of albumin in serum or plasma based on BCG method Autozyme Albumin is a single reagent system, ready to use. Autozyme Albumin is linear up to 6 gm% Albumin can be determined in 1 minute at room temperature The shelf-life of Autozyme Albumin is 18 months Pack Size : 2 x 50 ml Principle Serum albumin in the presence of Bromocresol-green under acidic condition forms a green coloured complex, The absorbance of this complex is proportional to the albumin concentration in serum or plasma. Quality Control To ensure adequate quality control, it is recommended that each batch should include a normal and an abnormal commercial reference control serum,. it should be realized that the uSe of quality control material checks both instrument and reagent functions together. Factors which might affect the performance of this test include proper instrument function, cleanliness of glassware and accuracy of pipetting. Other Details The reagents are for in vitro diagnostic use. BCG reagent and standard should be stored at temperature indicated on the bottle label.

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Clinical Chemistry

Acid Phosphatase Diagnostic Reagent (Pack size: 8 x 1 ml) from Accurex. Acid Phosphatase is used in accordance with ISO 14189 to detect acid phosphatase from Clostridium perfringens. Autozyme Acid Phosphate reagent is set for determination of Acid Phosphatase activity based on Kinetic method using a-naphthyl phosphate. In acidic pH of the buffer system, the reagent hydrolyses a-naphthyl phosphate to a-naphthol & phosphate. Accurex has gained considerable expertise in manufacturing & marketing of In-vitro Diagnostic reagents. About Autozyme Acid Phosphate is a reagent set for determination of Acid Phosphatase activity based on Kinetic method using a-naphthyl phosphate Autozyme Acid Phosphate is a single reagent system using one step procedure Autozyme Acid Phosphate can be determined in just 8 minutes at 37 degree C Acid Phosphate can be used on any Spectrophotometer, Discrete semi automated and Automated Analyzer. Programme can be designed for any specific analyzer upon request. Pack Size : 8 x 1 ml Principle In acidic pH of the buffer system, Acid Phosphatase hydrolyses a-naphthyl phosphate to a-naphthol and phosphate. The o-naphthol is then coupled with Diazotized Fast Red TR to form a Diazo dye which has strong absorbance at 405 nm. The increase in absorbance is directly proportional to the level of acid phosphatase in serum. The addition of L-Tartrate inhibits prostatic acid phosphatase but does not inhibit other isoenzymes. The activity of Prostatic Acid Phosphatase is obtained by subtracting the result of Non prostatic Acid phosphatase (Determination with Tartrate) from Total Acid Phosphatase (without tartrate). Quality Control To ensure adequate quality control it is recommended that each batch should include a normal and an abnormal commercial reference control serum. It should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect ne performance of this test includes proper instrument function, temperature control, cleanliness of glassware and accuracy of pipetting.

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Hemostasis Analyzer

Product Description: It’s a modern and advanced analyzer in Hemostasis. This single channel coagulation analyzer redefines the benefits in its class Erba. ECL 105 can perform PT, APTT, Fibrinogen, Thrombin Time, All Factiors, Lupus and DDimer. Product Features: Clotting Tests such as PT, aPTT, Fibrinogen, Thrombin time, Factors, Lupus anticoagulant performed using Light scatter principle Tests like D Dimer performed using Immuno-turbidimetry principle Interactive touch screen interface Clotting Graph provides details of the clotting testCuvette and reagent management software Twelve levels of QC with Levy-Jennings Plot- Identifies random and systematic errors Temperature stability at 37 degree C to perform the tests. Low Reagent Consumption USB Connectivity CE mark Product Applications: ECL 105 has uses in various routine IVD labs for doing routine PT and aPTT It has application in Blood Banks for Quality Control of Fibrinogen and Factor VIII It is used as Standby to bigger systems, in accredited centres It is used in Research Facilities to perform PT and aPTT on animal samples such as rat, mouse, rabbit, hamsters etc Key Specifications: Single channel semi-automated hemostasis system It can analyze 1 test at a time Sample id can be 14 digits alphanumeric, with progressive id or custom id options It is also possible to have a second position of assay preparation/incubation during the analysis of the current one, using preparation line option Optically detects and automatically moves to the next assay steps and auto starts the measurements Tests principles: Clotting (scattered light at 640nm) Immuno-turbidimetric (turbidimetry at 800nm) Dimensions / Weight: Dimension : 216 x 205 x 75 mm Weight : ~1 kg Environmental requirements: Operating Temperature : 17-32°C Humidity: Max. 80% Relative Humidity, non-condensing Power: Power Supply : 100-240 VAC and 50/60 Hz Power Consumption : 45 Watts In-Rush Power : 150 VA or less Calibrations: Up to 6 calibration levels per assay Storage of the active calibration curve Quality Controls: Up to 12 different control total can be assigned to any given assay Automatic Levey-Jennings plotting Automatic statistics calculation Storage of Quality Control results Stored Results: Independent storage allocation in the instrument memory for Quality Control (QC) and patient determinations Up to 1000 results for QC determinations Up to 1000 results for patients New results automatically replace the oldest results of the appropriate category past the maximum storage allowance Reaction curves are exclusively stored on the external USB pen drive. Regular backup and file purging is recommended from the USB pen drive to insure rapid operations. USB pen drive, FAT32 formatted

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Clinical Chemistry

ADVIA 2400 Chemistry System The right balance of speed and efficiency The ADVIA® 2400 Clinical Chemistry System manages the most demanding workloads and meets high turnaround-time (TAT) goals. Its menu includes methods for testing drugs-of-abuse, therapeutic drugs (TDM) and new assays such as cystatin C and CardioPhase® hsCRP. The ADVIA 2400 Clinical Chemistry System offers: High throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage heavy workloads Rapid, consistent, 2-second cycle time for faster tube speed and test throughput User-defined automatic repeat, dilution, and reflex testing Large onboard reagent capacity and optional concentrated reagents help to minimize intervention demands Refrigerated onboard storage of controls and reagents for extended stability and increased productivity Automation-ready design: no additional hardware required Features & Benefits The ADVIA 2400 Clinical Chemistry System meets today’s high turnaround-time goals with a throughput of up to 2400 tests/hour. In addition to assays for general and specialty chemistries, its menu includes assays for specific protein measurement, drugs-of-abuse testing (DAT), and therapeutic drug monitoring (TDM). Interesting new assays such as cystatin C, HbA1c with automated sample pretreatment, and CardioPhase® hsCRP can now be included in your routine testing. The ADVIA 2400 Chemistry System pushes productivity levels while maintaining the reliability and stability that keep laboratories up and running. A rapid, 2-second probe cycle time maximizes tube speed and test throughput and combines with the system’s efficient automation-readiness to provide the turnaround time needed for high-volume laboratories Superior Speed and Productivity Throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage the heaviest workloads Rapid, consistent, 2-second cycle time Throughput of 200 tubes per hour, even when running three ISE tests and nine photometric tests per sample Automatic Sample Retain technology, auto-repeat, auto-dilution, and auto-reflex testing Automation-ready Point-in-space aspiration enables connectivity to a track. Redundant sample loading provides built-in backup and easy handling of non-routine samples. Direct sampling from track prevents tubes being detained at an analyzer and reduces aliquoting. Minimal Need for Operator Intervention Minimal-maintenance ISEs Large onboard reagent capacity and optional concentrated reagents for fewer interruptions No-maintenance, 37°C incubation oil bath Auto-calibration and auto-QC from refrigerated onboard calibrators and controls Microvolume technology with 32,000 tests onboard and up to 60 days' onboard stability for improved walkaway time. Concentrated reagents for increased maximum capacity. Remote diagnostics and Inter-Laboratory Quality Control (ILQC) options Exceptional Reliability Sample integrity check for icterus, hemolysis, and lipemia Sample probe with automatic clot/clog detection, liquid-level sensing, short-sample detection, and crash protection Advances in onboard reagent stability, calibration frequency, reduction in interferences, and expanded assay linearity

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