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Clinical Chemistry

ADVIA Chemistry XPT System An advanced, automated clinical chemistry analyzer for high-volume laboratories The ADVIA® Chemistry XPT System provides timely, reliable results with continuous operation to meet the chemistry workloads of the most demanding laboratories. Delivers high throughput of up to 2400 tests per hour. Manages comprehensive testing with a menu of more than 115 assays. Improves workflow using automation and system technologies such as micro-volume and aliquot retention. Features & Benefits The ADVIA Chemistry XPT System*** is engineered for continuous operation and timely, accurate results—supporting you to reach your full potential today and be prepared for tomorrow. With an advanced user interface that is easy to use and VeriSmart Technology to support accuracy of testing, the ADVIA Chemistry XPT System predictably and consistently delivers timely, reliable results to meet expanding workloads. Simplified, Continuous Operation Simplify operation and training with the intuitive, icon-driven user interface. Extend walkaway times with concentrated reagents that provide high test capacity onboard. Quickly load most system fluids on the fly. Automate calibration, QC, startup, and shutdown. Consistent, Predictable Turnaround Time and Accuracy Offer a comprehensive chemistry menu of over 115 assays, including general and specialty chemistry, DAT, TDM, and specific proteins. Push productivity with a throughput of up to 2400 tests per hour (1800 photometric, plus 600 ISE). Control testing: STAT and specialty samples can always be front-loaded while an automation track is running. Designed for Automation Adapt and grow with direct connectivity to Siemens Healthineers and . Simplify your laboratory operations with connectivity to IT solutions including , , and . Increase productivity and efficiency with direct-from-track sampling and onboard aliquoting that allows samples to be immediately released to the next workstation. Do More with Less Reduce blood-draw requirements with micro-volume technology that uses a single 30 μL sample for up to 15 tests. Eliminate sample callback with automated, pre-programmable dilution, reflex, and rerun testing that uses an onboard aliquot. Improve workflow and accuracy with VeriSmart echnologies that perform hardware and software checks at all stages of sample processing.

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Rapid Test

The OnSite Troponin I Combo Rapid Test is a lateral flow chromatographic immunoassay for the qualitative detection of cardiac Troponin I (cTnI) in human serum, plasma or whole blood at a level equal to or higher than 1 ng/mL. It can be performed within 15 minutes by minimally skilled personnel, and without the use of laboratory equipment. The OnSite Troponin I Combo Rapid Test is intended to be used by healthcare professionals as an aid in the diagnosis of acute myocardial infarction (AMI). Any use or interpretation of this preliminary test result must also rely on patient’s symptoms and the professional judgment of a physician. A more precise test method such as an instrument method must be used to confirm the test result obtained by this device. Normally the level of cTnI in the blood is very low. cTnI is released into the blood stream in forms of free cTnI and cTnI-C-T complex at 4-6 hours after myocardial cell damage. The elevated level of cTnI could be as high as 50 ng/mL during 60-80 hours after AMI and remains detectable for up to 10-14 days post AMI. Therefore, circulating cTnI is a specific and sensitive marker for AMI. Clinical performance: Relative Sensitivity: 95.8% (95% CI: 91.5-97.9%) compared to a reference CLIA Relative Specificity: 99.7% (95% CI: 98.8-99.9%) Analytical sensitivity: The detection limit of cTnI is 1.0 ng/mL or greater in serum, plasma or whole blood specimen Cross-reactivity: No cross reactivity with 10 µg/mL skeletal muscle TnI, 2,000 ng/mL cardiac muscle TnT, 20 µg/mL cardiac muscle Myosin Dose hook effect: No hook effect was observed for cTnI at concentrations up to 3,521 µg/mL Interference: No interference was seen with 20 mg/dl Acetaminophen, 20 mg/dl Acetylsalicylic acid, 10.5 g/dl Albumin, 20 mg/dl Ascorbic acid, 1,000 mg/dl Bilirubin, 20 mg/dl Caffeine, 800 mg/dl Cholesterol, 200 mg/dl Creatinine, 20 mg/dl Gentistic acid, 1,000 mg/dl Hemoglobin, 600 mg/dl Oxilic acid, 1,600 mg/dl Triglycerides Shelf life: 24 months Individually sealed foil pouches containing: One cassette device One desiccant Plastic droppers Sample diluent (REF SB-R3002, 5 mL/bottle) One package insert (instruction for use) CTK Products at a Glance Insert MedlinePlus: Troponin Test Poster

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Glucometer

Item Description The Accu-Chek Softclix lancing device can help make lancing easy. Its rotatable cap offers 11 fixed depth settings for different skin types. Clixmotion technology minimizes any painful side-to-side motion of the lancet, which is why this lancing device is virtually pain-free to use. Benefits and features Virtually pain-free lancing Clixmotion technology controls the lancet’s movement Less side-to-side motion of the lancet means less skin damage Turn the rotatable cap for 11 penetration depth settings for different skin types The Accu-Chek Softclix lancets are precisely manufactured for precise entry Additional specifications Penetration Depth: 11 fixed-depth options, set with the rotatable cap Penetration Range: 0.8 to 2.3 mm Lancing Technology: Clixmotion Technology Weight: 21 g Alternative Site Testing: AST cap provided Needle Diameter: 0.4 mm Gauge: 28 Coating: Silicon How to use the Accu-Chek Softclix lancing device The Accu-Chek Softclix lancing device is small and easy to operate, with one-hand priming and lancing. Pull off the cap. Insert a new lancet into the lancet holder and push it in until it clicks. Press the cap on again until it clicks. Rotate the cap until the desired penetration depth is set. Press the priming button down until it clicks. Press the lancing device firmly against the side of the fingertip. Press the yellow release button. After measuring your blood glucose, pull off the cap and slide the ejector forwards to remove the lancet.

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Glucometer

Item Description The Accu-Chek Safe-T-Pro Uno lancing device keeps up with increased safety and hygienic requirements by health authorities, legislators, and health institutions. At the same time, it provides an ergonomic handling, lancing in just 3 milliseconds, and safety features that prevent accidental needle sticks. Its pre-set lancing depth makes it ready to use immediately. Benefits and Features Ready to use with a pre-set depth setting Safe-T-Technology ensures the needle is always safely stored away Stored needle prevents accidental needle sticks Ergonomical and easy to grip for safe handling Hygienic - each lancet can only be used once Beveled needle and small diameter for virtually pain-free blood sampling Equally suitable for right and left-handed use After a single use, the complete lancing device is disposed of Additional specifications Pre-fixed depth setting: Yes Penetration depth: 1.5 mm Needle diameter : 0.36 mm (28 G) Special needle cut: 3-facet cut Siliconized needle: Yes Sterility : 4 years after sterilization Single-use only: Yes Automatic retraction of needle : Yes Recognition of used device : Yes Intuitive handling : Yes How to use the Accu-Chek Safe-T-Pro Uno Simple, 2-step lancing Twist the sterility cap one quarter turn and remove it. Hold the lancing device between your index finger, middle finger, and thumb. Press the lancing device firmly against the chosen puncture site. Using your thumb, press the release button down completely. Move the lancing device away from the puncture site and discard it.

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Glycohemoglobin Analysis

Buy Xpress Glucometer Plus Kit Online, it’s a smart Glucometer Machine kit. This Digital Glucometer consists of 1 Blood Glucose Meter, 10 Test Strips, 1 Multilet Lancing Device, 10 Sterile Lancets, 1 Carry Pouch, 1 Warranty Card, Test Strip Insert Sheet, 1 Battery (3V) Gluco Plus Meter is intended for use in the home & in clinical settings. There are different types of Glucometers in Point of Care (POC). XPRESSGLUCO + meter measures the strength of the electrical current, calculates your blood glucose level and then displays your result in either milligrams of glucose per deciliter (mg/dL) or millimoles of glucose per liter (mmol/L). The system is intended for use outside the body (in vitro diagnostic use only). It should be used only for self-testing blood glucose (blood sugar) and only with fresh capillary whole blood samples drawn from the fingertips, forearm, upper arm, palm, calf or thigh. The system is intended for use in the home and in clinical settings. The system should not be used for the diagnosis of diabetes or for the testing of newborns. Blood glucose is measured by an electrical current that is produced when a blood samples mixes with the reagent (special chemicals) of the test strip. The electrical current changes with the amount of glucose in the blood sample. The XPRESSGLUCO+ meter measures the strength of the electrical current, calculates your blood glucose level and then displays your result in either milligrams of glucose per deciliter (mg/dL) or millimoles of glucose per liter (mmol/L). Safety Information 1. The user should not take any decision of medical relevance without first consulting his or her medical practitioner. 2. Call your doctor immediately if you experience symptoms that are not consistent with your blood glucose test results. 3. High altitudes above than 3,402 meter (11,161 ft) may affect the test results. 4. Temperatures outside the range of 10°C to 40°C (50°F to 104°F) may affect the test results. Do not test beyond of temperature range. 5. Do not perform servicing and maintenance while the meter is in use. 6. No modification of this equipment is allowed. 7. Do not use this meter near cellular or cordless telephones in a call, walkie-talkies, garage door openers, radio transmitters, or other electrical or electronic equipment that are sources of electromagnetic, radiation, as these may interfere with the proper operation of the meter. Direction for Use 1. Wash you hands and puncture sit: Wash your hands in warm, soapy water. Rinse and dry completely . Warm your fingers to increase blood flow. 2. Insert Test Strip : Remove a new test strip from vial. Be sure to tightly replace vial cap after removing test strips. Insert a test strip with the contact bar end entering into the test strip slot first. Push the test strip as far as it will go without bending it. The meter turns on automatically. 3. Hold the prepared lancing device firmly against the side of your fingertip. Press the release button. (NOTE : If you want to do alternative site testing, please refer to the “About Alternative Site Testing (AST)” section. Please consult your healthcare professional before obtaining blood from site other than your fingertip.) 4. Obtain a Blood Sample : Gently massage your finger or puncture site to obtain the required blood volume. To perform the test, you need only 0.5 μL of blood sample. Do not smear the blood sample. To obtain best accurate result, wipe off the first drop of blood and gently squeeze another drop of blood. 5. Apply Blood Sample : When the meter shows the “ ” symbol, apply blood to the opening of the absorbent channel of the test strip where it meets the narrow channel. Blood will be drawn into the test strip. If the test strip confirmation window is full, you will hear a beep. 6. Read Your Result : After the meter counts down from 5 to 1, your blood glucose test result appears along with the unit of measure, date and time. Test result is lower than the target range Test result is within the target range. Test result is higher than the target range *The default target range is 70 mg/dl to 180 mg/dl. 7. Turn Off the Meter : This blood glucose result is automatically stored in the meter memory. Turn the meter off by removing the test strip. Discard the used test strip carefully to avoid contamination. 8. After use, twist off the Lancing Device Cap. Push the exposed tip of the lancet into its Protective Cap. 9. Slide the Lancet Ejector forward and disposing the used lancet in an approved container. Discard the used lancet according to your country’s safety regulations. Replace the Lancing Device Cap. Other Info •Use only XPRESSGLUCO+ Control Solution with your XPRESSGLUCO+ meter. •Check the expiration date on the bottle. Do not use if expired. •Use within a period of 90 days from the date that you first open it. Record the discard date on the control solution bottle when you first open it to serve as a reminder to discard after 90 days. •The control solution ranges are printed on the label of the XPRESSGLUCO+ Blood Glucose Test Strip vial. They are not recommended target ranges for your blood glucose. •For in vitro diagnostic use. •Do not add any liquid to the XPRESSGLUCO+ Control Solution. •Do not take internally or inject.

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Clinical Chemistry

Infinite Liquid a-Amylase 12 ml Diagnostic Reagent from Accurex (Pack Size : 6 x 2 ml). a-Amylase reagent is used for determination of amylase activity based on kinetic method using Gal G2 – a CNP. Amylase is a ready-to-use reagent. Normal amylase level is 40 to 140 units per liter (U/L) or 0.38 to 1.42 microkat/L (µkat/L). Infinite a-Amylase can be used on any Spectrophotometer, Discrete semiautomated & Automated analyzers. Reaction type is Kinetic. Accurex Biomedical is the first biochemical reagents manufacturing company in India About Infinite a-Amylase ‘is a reagent set for determination of amylase activity based on kinetic method using Gal G2 – a CNP. Infinite a-Amylase is a ready-to-use reagent. Infinite a-Amylase can be determined in just 21/2 minutes at 37°C. Infinite a-Amylase is linear upto 2000 IU/1. Infinite a-Amylase is a High Stability Reagent. Infinite a-Amylase can be used on any Spectrophotometer, Discrete semiautomated and Automated analyzers. Programme can be designed for any specific analyzer upon request. Pack Size : 6 x 2 ml Principle Amylase test involves use of a chromogenic substrate Gal G, – a CNP (2-chloro-4-nitrophenyl linked with galactosyl maltoside). The direct action of amylase with this substrate results in the release of more than 90% of 2-chloro-4-nitrophenol, which can be monitored by kinetic assay at 405 nm. The increase in absorbance is directly proportional to the amylase activity in the sample. Quality Control To ensure adequate quality control, it is recommended that each batch should include a normal and abnormal commercial reference control serum. It should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect the performance of this test include proper instrument function, temperature control, cleanliness of glassware and accuracy of pipetting. Other Details Mix thoroughly and transfer the assay mixture immediately to the thermostated cuvette and start the stopwatch simultaneously. Record the first reading at 60 second and subsequently three more readings with 30 seconds interval at 405 nm.

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