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Clinical Chemistry

ADVIA 2400 Chemistry System The right balance of speed and efficiency The ADVIA® 2400 Clinical Chemistry System manages the most demanding workloads and meets high turnaround-time (TAT) goals. Its menu includes methods for testing drugs-of-abuse, therapeutic drugs (TDM) and new assays such as cystatin C and CardioPhase® hsCRP. The ADVIA 2400 Clinical Chemistry System offers: High throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage heavy workloads Rapid, consistent, 2-second cycle time for faster tube speed and test throughput User-defined automatic repeat, dilution, and reflex testing Large onboard reagent capacity and optional concentrated reagents help to minimize intervention demands Refrigerated onboard storage of controls and reagents for extended stability and increased productivity Automation-ready design: no additional hardware required Features & Benefits The ADVIA 2400 Clinical Chemistry System meets today’s high turnaround-time goals with a throughput of up to 2400 tests/hour. In addition to assays for general and specialty chemistries, its menu includes assays for specific protein measurement, drugs-of-abuse testing (DAT), and therapeutic drug monitoring (TDM). Interesting new assays such as cystatin C, HbA1c with automated sample pretreatment, and CardioPhase® hsCRP can now be included in your routine testing. The ADVIA 2400 Chemistry System pushes productivity levels while maintaining the reliability and stability that keep laboratories up and running. A rapid, 2-second probe cycle time maximizes tube speed and test throughput and combines with the system’s efficient automation-readiness to provide the turnaround time needed for high-volume laboratories Superior Speed and Productivity Throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage the heaviest workloads Rapid, consistent, 2-second cycle time Throughput of 200 tubes per hour, even when running three ISE tests and nine photometric tests per sample Automatic Sample Retain technology, auto-repeat, auto-dilution, and auto-reflex testing Automation-ready Point-in-space aspiration enables connectivity to a track. Redundant sample loading provides built-in backup and easy handling of non-routine samples. Direct sampling from track prevents tubes being detained at an analyzer and reduces aliquoting. Minimal Need for Operator Intervention Minimal-maintenance ISEs Large onboard reagent capacity and optional concentrated reagents for fewer interruptions No-maintenance, 37°C incubation oil bath Auto-calibration and auto-QC from refrigerated onboard calibrators and controls Microvolume technology with 32,000 tests onboard and up to 60 days' onboard stability for improved walkaway time. Concentrated reagents for increased maximum capacity. Remote diagnostics and Inter-Laboratory Quality Control (ILQC) options Exceptional Reliability Sample integrity check for icterus, hemolysis, and lipemia Sample probe with automatic clot/clog detection, liquid-level sensing, short-sample detection, and crash protection Advances in onboard reagent stability, calibration frequency, reduction in interferences, and expanded assay linearity

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Clinical Chemistry

The Autochem Xact Pro is a Fully Automatic Random Access Clinical Chemistry Analyzer. It is a compact, benchtop analyser with throughput up to 200 tests per hour. First-in-Class On-board Warm-water Laundry System Probe with Collision-Protection System Multi function Probe which works as mixer also Probe with Capacitance based liquid level sensor Robust Multi-functional Software Intelligent" Mixing Arm Removable & flexible Sample - Reagent Disc with 40 Open position for reagent & samples respectively. DESIGNED FOR UNINTERRUPTED WORK FLOW OTHER FEATURES ROBUST MULTI-FUNCTIONAL SOFTWARE Probe with Collision-Protection System Both horizontal and vertical collision protection ensures that system re-starts testing after any unwanted physical intervention. This prevents wastage of reagents, saves test time and increases life of probe Multi functional Probe Probe has flexibility to work even as a mixer in case in-built mixer does not work Probe with Capacitance based liquid level sensor Probe with liquid level sensor checks and indicates the presence of adequate sample or reagent in the container before starting testing process. Thus prevents unwanted interruptions in testing process “Intelligent” Mixing Arm User defined, variable three level mixing speed ensure thorough mixing Accurate performance of regular and immunoturbidimetric assays Independent cleaning station for mixer which prevents carry-over ensuring high precision Removable & flexible Sample – Reagent Disc 40 Open position for reagent & samples respectively Facility to use primary & variable sample cup as well as non fixed position for Sample, Control, Calibrator & STAT samples Two bottle sizes of 18 mL or 5 mL with unique design to reduce reagent dead volume Optional internal Reagent & Sample barcode reader makes the operation user friendly & ensure correct result reporting Reaction tray 60 reusable plastic reaction cuvettes which is also scanned before performing the test which means less recurring cost without compromising on quality. To assure precise results Individual replacement of cuvette offer lower consumable cost REFLEX Testing Functionality Allows user to program Low & High panic value for a particular test which triggers auto-testing of assigned tests which ensures faster and comprehensive reporting Dynamic & Real-time display of Test Running Status for quicker decision making Running status of reagent tray, Sample tray & reaction tray Real-time monitoring of Reaction curve On board inventory management Real-time monitoring of reagent residual volume saves reagent cost & time In-built full QC Program Provision to run 3 levels of control with Levey Jennings graph which gives confidence in reporting with multiple rules (1SD, 2SD and 3SD) Reagent, Calibrator & Control lot monitoring User friendly Bi-Directional LIS Interface

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Clinical Chemistry

TURBOCHEM MAGNA Constant throughput of 300 Tests/hour Discrete random access Bench Top Biochemistry analyzer Independent Probe for Reagents and Sample. Dedicated mixer which enhances faster mixing of reagents and sample High precision results with Low CV% Probe crash prevention with high sensitive liquid level detection of sample/reagents On board laundry with 5 stages of washing Intelligent QC management Bidirectional LIS connectivity Minimal consumable cost for instrument maintenance Remote maintenance, interactive trouble shooting with online application support Constant Throughput of 300 Test/Hour: Guarantees output in any combination Reagent and Sample Tray: Loading more reagent and sample at same time. Intelligent QC Management: Enable QC rules that suit you. Bi-Directional LIS Connectivity: Ensures superior lab process. Specially Designed Mixer: Ensure Homogeneous mixing of reagent and sample.

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Clinical Chemistry

MACHINE-TURBOCHEM PRIME Constant throughput of 180 Tests/hour Discrete random access Bench Top Biochemistry analyzer Probe crash prevention with high sensitive liquid level detection of sample/reagents High precision results with Low CV% Constant throughput of 180 T / Hr Consistently delivering high precision results with low CV% Performs wide range of biochemistry & immunoturbidimetry assays Robust performance with interchangeable reagent position Lowest reaction volume that saves samples and reagents for more number of tests Probe crash prevention with high sensitive liquid level detection of sample/reagents Online condition monitoring, real time fault detection and interactive troubleshooting with i-track QC rules that suits any laboratory requirements Bidirectional LIS connectivity 60 Reagent position assures that the more assays could be performed On board laundry with 5 stages of washing Intelligent QC management 60 Reagent position assures that the more assays could be performed Bidirectional LIS connectivity Minimal consumable cost for instrument maintenance Remote maintenance, interactive trouble shooting with online application support

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Clinical Chemistry

Best Fully Automated Clinical Chemistry Analyzer – Sphera M from Accurex. This chemistry analyzer is made in Italy & provides Accurate, Precise and Rapid Testing Solution. Sphera M is a Compact, fully automated, open random-access analyzer. The Minimum reaction volume is 210 µl, Minimal < 1L/h water consumption, 80 reusable UV transmitting Bionex® plastic cuvettes, 8-step wash station. It has Removable refrigerated tray with 30 open reagent positions for 50 ml or 20 ml bottles. Multiple virtual reagent disks can be programmed. The Chemistry analyser also does Auto-wash of inner & exterior probe surface. QUALITY CONTROL & CALIBRATION QUALITY CONTROL: • Levey-Jennings plots and Westgard multi rules • Upto 3 QC levels per test • QC monitor and reports • Method statistics: Test counter, CV%, mean, graphical trend analysis CALIBRATION: • Method and reagent monitor (volumes, available tests, calibration, QC status) • Automatic pre-dilution for calibrators • Upto 8 calibrators per method • Auto recalculation of result using last calibration. UNIQUE SOFTWARE DESIGN AND ARCHITECTURE: • Software designed for touch screen use • Intuitive user interface • Continuous loading of samples and reagents • Random-access and STAT • Free choice of execution order • Extended walk-away capability • Results archive with cumulative charts • Programmable automatic start up routine • Multiple work lists INTERFACE: • Bi-directional LIS, ASTM, over ethernet port of the external PC • Positive identification of samples with internal barcode reader (optional) • Printing on any Windows 7®/8® compatible printer • Method defined washing programs SYSTEM PACKS FOR SPHERA™ Accurex has developed dedicated system packs for Sphera™. Our biochemistry reagents have been intensively evaluated and validated to achieve the highest performance in Sphera™. Accurex recommends the use of these system packs according to instructions and applications validated by Accurex. Safety Information 8-step wash station for thorough cleaning of each cuvette (Needles: 6 dispensing, 6 aspiration, 1 cleaning) • Two types of systemic and special washing solutions for removing obstinate probe residues Direction for Use QUALITY CONTROL • Levey-Jennings plots and Westgard multi rules • Upto 3 QC levels per test • QC monitor and reports • Method statistics: Test counter, CV%, mean, graphical trend analysis CALIBRATION • Method and reagent monitor (volumes, available tests, calibration, QC status) • Automatic pre-dilution for calibrators • Upto 8 calibrators per method • Auto recalculation of result using last calibration Other Info Accurex has developed dedicated system packs for Sphera™. Our biochemistry reagents have been intensively evaluated and validated to achieve the highest performance in Sphera™. Accurex recommends the use of these system packs according to instructions and applications validated by Accurex.

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Clinical Chemistry

Best Semi Automatic Biochemistry Analyzer AT Smart from Accurex. AT SMART is a Biochemistry/Clinical Analyzer with a user-friendly and the human interface is via touch screen. It measures the optical densities of samples & calculates the sample concentration which are used for biochemical investigation. This Biochemistry Machine operates from near UV to visible range. Semi Auto Analyzer AT SMART is CE certified and has undergone rigors testing before being delivered to customers. About •SMART MAINTENANCE •SMART LIS •SMART INVENTORY MANAGEMENT REDUCED ERRORS: IT allows for the accurate collection of data, automated workflows & minimized waste. SAVES TIME: Patient monitoring can be done in real-time, saves engineers visiting time. BETTER PATIENT EXPERIENCE: A connected laboratory system creates an environment that meets each patient’s needs. INSTRUMENT BREAKDOWN MANAGEMENT: Real-time data helps to monitor instrument performance. ONLINE REACTION CURVES: • Real time reaction curve with special • Flagging gives confidence in patient reports. INTELLECTUAL SOFTWARE: • User friendly Device. • 150 Direct access test keys gives freedom to select parameters easily. • Availability of different assay modes. DRY BATH INCUBATOR: • Dry bath incubator with 12 test tube positions • Mini size with 15 minutes start up time FEATURES: •Remote access & monitoring via Internet •150 test parameters •Built-in thermal printer to print results, enzymatic curves and standard calibration curves •Large graphic display with real time graph display for enzymatic reaction •Touch screen interface with dynamic test access key SPECIFICATIONS: Methodology- • Absorbance • Endpoint with standard, factor, sample blank & diffrential • Two-point (fixed time) and multi point kinetics • Multi standard calibration • Mono or bi-chromatic reading • Turbidimetry Optical System- • Principle: photometry • Range of measurement: 0.0-3.0A • Spectral range selection: Automatic via filter wheel • Filters: 340, 405, 505, 546, 578 and 630 nm plus two free position • Bandwidth:10nm (+/- 2nm) • Light source: Life Long Halogen lamp • Blanking: Automatic • Detector: Silicon Photodiode Photometer- • Peltier regulated 25ºC, 30ºC and 37ºC • Flow cell of 18 µ L • Continuous flow system with peristaltic pump • Programmable Sipping Volume Memory- • 150+ User Defined Test Programs • 1000 test results in instrument memory and unlimited test resultresult storage via cloud • Reagent Blank • 2 Level of QC Quality Control- • Levy-Jennings chart using westgard’s rules • 30 Normal and abnormal QC values for selected test User Interface- • Graphic LCD back Lit 240×64 pixels • Touch Screen input • Data port and cloud connectivity • Type : Graphic thermal printer Power & Dimensions- • Voltage : 220 V • Frequency : 50 Hz • Maximum power : < 150 VA • Maximum relative humidity : 75% • Compact form factor • Weight: < 6kgs Safety Information Precautions • Instrument should be operated only by authorised or trained personnel • For any reasons, unauthorised personnel should not be engaged for servicing or removing the cabinet • Power source should be regulated either by voltage stabilizer or regulated power back up (UPS). If inverter is been used, please ensure there exists a voltage stabilizer • Reagents recommended by the company to be preferably used • Flow cell needs to be rinsed regularly with the company recommended flow cell cleaning solution • User is requested not to use any other pointing devices other than being supplied by company while operating touch screen • The operating environment should be clean and protected from direct sunlight • During the day at the end of the work, it should be ensured that flow cell is always filled with distilled water • During transport / longer duration of shut down, th Direction for Use Please ensure that the power source is properly grounded and voltage between Line and Ground is less than 2V AC – 5V AC. • Please ensure that the instrument is placed on a firm table, clean environment, and sufficient ventilation space. • Switch On the instrument. • Instrument will run its own internal diagnostic routines, to ensure proper working of critical functions. • Allow the instrument to stabilize for 10 minutes. • During the stabilization time, please wash the flow cell with cleaning solution and distilled water for at least two times. • During shut down, ensure that the flow cell is cleaned with flow cell cleaning solution and rinsed thoroughly using distilled water. • For overnight shutdown, please ensure flow cell is filled with distilled water. • Cover the instrument with the given dust cover Other Info GENERAL INFORMATION While installing and setting up the instrument, few safety warnings and general precautions described in the further sections must be observed. A. Power Supply : • Power source should be grounded and have either servo stabilizer or regulated power back up • Power cord should be CE , CSA and UL marked • Voltage : 115 – 230 Volts ± 10% 50 – 60 Hz • Grounding: Make sure that electrical power source is properly grounded.

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Clinical Chemistry

The HumaStar 80 is a clinical chemistry analyzer that combines the low maintenance effort of photometers with the convenience of automated sample processing. Its key features include autodiagnosis for electronic and mechanical components, emergency sample analysis and LIS interface. Highlights Original instrumentation provided by Human Diagnostics Diamond Down-To-Frame® refurbishment provided. Refurbishment includes disassembly and total restoration. Process continues with assembly, repair, and diagnostics. Certification concludes with calibration, QC and QA validation. Contact Diamond for pricing, specifications and availability. Assays Total assays tested: 48 - Acid Phosphatase (ACP), Alanine Aminotransferase (ALT) Entry-level, optimized batch analyzer > Up to 80 tests per hour > 40 tests per hour typical> 20 reagents on board> 54 sample positions> 18 μl micro flow cell> STAT function> Intelligent optimized batch mode> English, French, Italian, Spanish software> Automatic re-run with sample dilution> Integrated maintenance schedule> Built-in QC management> Heated pipetting system> Dimensions: 72 x 73 x 45 cm > Net weight: 42 kg> 230/110 Vac, 350

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Clinical Chemistry

Product Specification Model Name/Number HumaStar 200 Brand Human Automation Fully Automatic Display Digital Dimensions 69 x 76 x 52 cm (WxDxH) Frequency 50/60 Hz Voltage 220-240 or 110-120 Vac Temperature 16-30 Degree C Throughput Up to 200 t/h throughput Weight 51 kg Reaction volume 210-350 il Wash station 6 dispensing needles Water consumption < 2 l/h (8 ml/test) Languages English, French, Spanish Software (other languages can be added) Humidity < 80 % non-condensing Data External computer required (Pentium IV, 2 GHz Mode Open, random-access, STAT Product Description Product Detail : Unique Random-Access Analyzers for Small to Medium Size Laboratories Unique design Unique software architecture Unique features Analysis Endpoint (bichromatic), Differential endpoint (with sample blank), Fixed time, Kinetic (bichromatic) Multi-standard (up to 8), factor, linear, non linear (cubic-spline, poly-linear and logit-log four parameters) Samples Removable sample tray 60 positions: primary tubes 12–12.5x100 mm and 10 mm cups Optional: sample tray for 20 primary tubes 12–16x100 mm and 20 cups 3.5 ml Sample volume: 2–300 µl Internal barcode reader Automatic pre- and post-dilution Test profiles and replicates Reagents Removable reagent tray 30 reagent / diluent positions 50 and 20 ml bottles, adapter for tubes and cups Reagent volumes: 5–350 µl Refrigeration to ~9 Degree C below ambient (at bottom of bottle) Substrates, Enzymatic, Turbidimetric Reaction Reaction volume: 210–350 µl 80 reusable Bionex® cuvettes 6 mm optical path Heat transfer by air Pipetting Needle shock detector Capacitive liquid level detector Wash station 8-step cuvette wash station Systemic and special washing solution HumaStar 200: 6 dispensing needles Water consumption < 2 l/h (8 ml/test) Optical system 9 discrete wavelengths (340, 405, 505, 546, 578, 600, 650, 700 nm, one free position) Band pass: +/– 5 nm Photometric linearity: 0–2.5 Abs Stability: <1 % drift per day Management 20 GB HDD, 512 MB RAM, CD/R, USB) Windows 7® with .NET framework 4.0 English, French, Spanish OS recommended Core i3TM or dedicated graphic card recommended Minimum 900 dots resolution Designed for touch screen (1280x1024 pixel) LIS: Bi-directional, polling mode, ASTM, ethernet Printouts By patient, single test, complete sample, work sheet, method and QCs, calibration curves, kinetics, continuous printing

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Hemostasis Analyzer

Product Description: It’s a modern and advanced analyzer in Hemostasis. This single channel coagulation analyzer redefines the benefits in its class Erba. ECL 105 can perform PT, APTT, Fibrinogen, Thrombin Time, All Factiors, Lupus and DDimer. Product Features: Clotting Tests such as PT, aPTT, Fibrinogen, Thrombin time, Factors, Lupus anticoagulant performed using Light scatter principle Tests like D Dimer performed using Immuno-turbidimetry principle Interactive touch screen interface Clotting Graph provides details of the clotting testCuvette and reagent management software Twelve levels of QC with Levy-Jennings Plot- Identifies random and systematic errors Temperature stability at 37 degree C to perform the tests. Low Reagent Consumption USB Connectivity CE mark Product Applications: ECL 105 has uses in various routine IVD labs for doing routine PT and aPTT It has application in Blood Banks for Quality Control of Fibrinogen and Factor VIII It is used as Standby to bigger systems, in accredited centres It is used in Research Facilities to perform PT and aPTT on animal samples such as rat, mouse, rabbit, hamsters etc Key Specifications: Single channel semi-automated hemostasis system It can analyze 1 test at a time Sample id can be 14 digits alphanumeric, with progressive id or custom id options It is also possible to have a second position of assay preparation/incubation during the analysis of the current one, using preparation line option Optically detects and automatically moves to the next assay steps and auto starts the measurements Tests principles: Clotting (scattered light at 640nm) Immuno-turbidimetric (turbidimetry at 800nm) Dimensions / Weight: Dimension : 216 x 205 x 75 mm Weight : ~1 kg Environmental requirements: Operating Temperature : 17-32°C Humidity: Max. 80% Relative Humidity, non-condensing Power: Power Supply : 100-240 VAC and 50/60 Hz Power Consumption : 45 Watts In-Rush Power : 150 VA or less Calibrations: Up to 6 calibration levels per assay Storage of the active calibration curve Quality Controls: Up to 12 different control total can be assigned to any given assay Automatic Levey-Jennings plotting Automatic statistics calculation Storage of Quality Control results Stored Results: Independent storage allocation in the instrument memory for Quality Control (QC) and patient determinations Up to 1000 results for QC determinations Up to 1000 results for patients New results automatically replace the oldest results of the appropriate category past the maximum storage allowance Reaction curves are exclusively stored on the external USB pen drive. Regular backup and file purging is recommended from the USB pen drive to insure rapid operations. USB pen drive, FAT32 formatted

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