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'internal diagnostic routines'

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Clinical Chemistry

Best Semi Automatic Biochemistry Analyzer AT Smart from Accurex. AT SMART is a Biochemistry/Clinical Analyzer with a user-friendly and the human interface is via touch screen. It measures the optical densities of samples & calculates the sample concentration which are used for biochemical investigation. This Biochemistry Machine operates from near UV to visible range. Semi Auto Analyzer AT SMART is CE certified and has undergone rigors testing before being delivered to customers. About •SMART MAINTENANCE •SMART LIS •SMART INVENTORY MANAGEMENT REDUCED ERRORS: IT allows for the accurate collection of data, automated workflows & minimized waste. SAVES TIME: Patient monitoring can be done in real-time, saves engineers visiting time. BETTER PATIENT EXPERIENCE: A connected laboratory system creates an environment that meets each patient’s needs. INSTRUMENT BREAKDOWN MANAGEMENT: Real-time data helps to monitor instrument performance. ONLINE REACTION CURVES: • Real time reaction curve with special • Flagging gives confidence in patient reports. INTELLECTUAL SOFTWARE: • User friendly Device. • 150 Direct access test keys gives freedom to select parameters easily. • Availability of different assay modes. DRY BATH INCUBATOR: • Dry bath incubator with 12 test tube positions • Mini size with 15 minutes start up time FEATURES: •Remote access & monitoring via Internet •150 test parameters •Built-in thermal printer to print results, enzymatic curves and standard calibration curves •Large graphic display with real time graph display for enzymatic reaction •Touch screen interface with dynamic test access key SPECIFICATIONS: Methodology- • Absorbance • Endpoint with standard, factor, sample blank & diffrential • Two-point (fixed time) and multi point kinetics • Multi standard calibration • Mono or bi-chromatic reading • Turbidimetry Optical System- • Principle: photometry • Range of measurement: 0.0-3.0A • Spectral range selection: Automatic via filter wheel • Filters: 340, 405, 505, 546, 578 and 630 nm plus two free position • Bandwidth:10nm (+/- 2nm) • Light source: Life Long Halogen lamp • Blanking: Automatic • Detector: Silicon Photodiode Photometer- • Peltier regulated 25ºC, 30ºC and 37ºC • Flow cell of 18 µ L • Continuous flow system with peristaltic pump • Programmable Sipping Volume Memory- • 150+ User Defined Test Programs • 1000 test results in instrument memory and unlimited test resultresult storage via cloud • Reagent Blank • 2 Level of QC Quality Control- • Levy-Jennings chart using westgard’s rules • 30 Normal and abnormal QC values for selected test User Interface- • Graphic LCD back Lit 240×64 pixels • Touch Screen input • Data port and cloud connectivity • Type : Graphic thermal printer Power & Dimensions- • Voltage : 220 V • Frequency : 50 Hz • Maximum power : < 150 VA • Maximum relative humidity : 75% • Compact form factor • Weight: < 6kgs Safety Information Precautions • Instrument should be operated only by authorised or trained personnel • For any reasons, unauthorised personnel should not be engaged for servicing or removing the cabinet • Power source should be regulated either by voltage stabilizer or regulated power back up (UPS). If inverter is been used, please ensure there exists a voltage stabilizer • Reagents recommended by the company to be preferably used • Flow cell needs to be rinsed regularly with the company recommended flow cell cleaning solution • User is requested not to use any other pointing devices other than being supplied by company while operating touch screen • The operating environment should be clean and protected from direct sunlight • During the day at the end of the work, it should be ensured that flow cell is always filled with distilled water • During transport / longer duration of shut down, th Direction for Use Please ensure that the power source is properly grounded and voltage between Line and Ground is less than 2V AC – 5V AC. • Please ensure that the instrument is placed on a firm table, clean environment, and sufficient ventilation space. • Switch On the instrument. • Instrument will run its own internal diagnostic routines, to ensure proper working of critical functions. • Allow the instrument to stabilize for 10 minutes. • During the stabilization time, please wash the flow cell with cleaning solution and distilled water for at least two times. • During shut down, ensure that the flow cell is cleaned with flow cell cleaning solution and rinsed thoroughly using distilled water. • For overnight shutdown, please ensure flow cell is filled with distilled water. • Cover the instrument with the given dust cover Other Info GENERAL INFORMATION While installing and setting up the instrument, few safety warnings and general precautions described in the further sections must be observed. A. Power Supply : • Power source should be grounded and have either servo stabilizer or regulated power back up • Power cord should be CE , CSA and UL marked • Voltage : 115 – 230 Volts ± 10% 50 – 60 Hz • Grounding: Make sure that electrical power source is properly grounded.

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Hematology

VES MATIC 5 is the next-generation automated module manufactured by Diesse Diagnostica (Italy), a highly advanced, Intelligent, Intuitive & Interactive Graphic user Interface for estimating ESR using EDTA samples. Product Features: Automated instrument for the determination of ESR directly from EDTA vacutainers Faster TAT by loading 216 sample tubes at a time Pediatric samples can be processed in microtainers Reliable results with Temperature correction facility Accurate results by eliminating manual HCT correction in Anaemic samples Real-Time monitoring of samples Detection of Lipemic, Hemolyzed, Coagulated samples Standardization in mixing with Inbuilt Mixer Analyser P. Code Product Name Pack size Vesmatic 5 165941 Next 5K Transponder 1x 5000 Vesmatic 5 165942 Next 10 K Transponder 1x 10000 Display - 19" Full HD (1920x1080) LCD with PCAP Touch Screen Peripheral Control - based on Everex distributed control system with peripheral motor control boards Operating system - Linux Analysis module - 89 Positions for Sample Tubes Sample Loading - up to 18 racks simultaneously Throughput - 190 samples per hour. First result after 28 minutes Walk away mode - Supported Continuous loading - Supported Sample mixing - with multiple 180° rotations of the tubes Collection of analysed samples - reinserted into the original loading rack LIS Connection - Multiple LIS connection protocols are available: ASTM / Proprietary Remote diagnostics - available via Ethernet connection. Printer -Alphanumeric with 58mm-wide thermal paper, 36 characters per line, speed 20 mm/sec. Imaging System - 2 high resolution cameras for sample identification and analysis; 1 standard camera for internal inspection Image processor - Dedicated Quad Core CPU with integrated GPU for real-time HD image processing of samples Temperature range in operation - from +15 to + 35°C; Storage from + 5°C to + 45°C Humidity range - from 20% to 80% without condensation Central unit - Quad core ARM Cortex A-53 CPU ARM Cortex A-53, 16 GB eMMC, 4 GB RAM Interfaces - 2 x RS232C, 2 Host USB, 1 Client USB, Ethernet Protection category - CLASS I Safety standard - EN 61010-1, EN 61010-2-081, EN 61010-2-101 EMC - EN61326-1 Installation category - II Mains voltage - 230VAC@50Hz; US/Canada: 110-120Vac@60Hz Electrical energy consumption - 420VA Fuse block - 2 x 5.0 AT (delayed) (5 x 20 mm) UL Dimensions (mm) - 850 (W) x 750 (H) x 830 (D) Weight - 80 kg

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Glycohemoglobin Analysis

Buy Xpress Glucometer Plus Kit Online, it’s a smart Glucometer Machine kit. This Digital Glucometer consists of 1 Blood Glucose Meter, 10 Test Strips, 1 Multilet Lancing Device, 10 Sterile Lancets, 1 Carry Pouch, 1 Warranty Card, Test Strip Insert Sheet, 1 Battery (3V) Gluco Plus Meter is intended for use in the home & in clinical settings. There are different types of Glucometers in Point of Care (POC). XPRESSGLUCO + meter measures the strength of the electrical current, calculates your blood glucose level and then displays your result in either milligrams of glucose per deciliter (mg/dL) or millimoles of glucose per liter (mmol/L). The system is intended for use outside the body (in vitro diagnostic use only). It should be used only for self-testing blood glucose (blood sugar) and only with fresh capillary whole blood samples drawn from the fingertips, forearm, upper arm, palm, calf or thigh. The system is intended for use in the home and in clinical settings. The system should not be used for the diagnosis of diabetes or for the testing of newborns. Blood glucose is measured by an electrical current that is produced when a blood samples mixes with the reagent (special chemicals) of the test strip. The electrical current changes with the amount of glucose in the blood sample. The XPRESSGLUCO+ meter measures the strength of the electrical current, calculates your blood glucose level and then displays your result in either milligrams of glucose per deciliter (mg/dL) or millimoles of glucose per liter (mmol/L). Safety Information 1. The user should not take any decision of medical relevance without first consulting his or her medical practitioner. 2. Call your doctor immediately if you experience symptoms that are not consistent with your blood glucose test results. 3. High altitudes above than 3,402 meter (11,161 ft) may affect the test results. 4. Temperatures outside the range of 10°C to 40°C (50°F to 104°F) may affect the test results. Do not test beyond of temperature range. 5. Do not perform servicing and maintenance while the meter is in use. 6. No modification of this equipment is allowed. 7. Do not use this meter near cellular or cordless telephones in a call, walkie-talkies, garage door openers, radio transmitters, or other electrical or electronic equipment that are sources of electromagnetic, radiation, as these may interfere with the proper operation of the meter. Direction for Use 1. Wash you hands and puncture sit: Wash your hands in warm, soapy water. Rinse and dry completely . Warm your fingers to increase blood flow. 2. Insert Test Strip : Remove a new test strip from vial. Be sure to tightly replace vial cap after removing test strips. Insert a test strip with the contact bar end entering into the test strip slot first. Push the test strip as far as it will go without bending it. The meter turns on automatically. 3. Hold the prepared lancing device firmly against the side of your fingertip. Press the release button. (NOTE : If you want to do alternative site testing, please refer to the “About Alternative Site Testing (AST)” section. Please consult your healthcare professional before obtaining blood from site other than your fingertip.) 4. Obtain a Blood Sample : Gently massage your finger or puncture site to obtain the required blood volume. To perform the test, you need only 0.5 μL of blood sample. Do not smear the blood sample. To obtain best accurate result, wipe off the first drop of blood and gently squeeze another drop of blood. 5. Apply Blood Sample : When the meter shows the “ ” symbol, apply blood to the opening of the absorbent channel of the test strip where it meets the narrow channel. Blood will be drawn into the test strip. If the test strip confirmation window is full, you will hear a beep. 6. Read Your Result : After the meter counts down from 5 to 1, your blood glucose test result appears along with the unit of measure, date and time. Test result is lower than the target range Test result is within the target range. Test result is higher than the target range *The default target range is 70 mg/dl to 180 mg/dl. 7. Turn Off the Meter : This blood glucose result is automatically stored in the meter memory. Turn the meter off by removing the test strip. Discard the used test strip carefully to avoid contamination. 8. After use, twist off the Lancing Device Cap. Push the exposed tip of the lancet into its Protective Cap. 9. Slide the Lancet Ejector forward and disposing the used lancet in an approved container. Discard the used lancet according to your country’s safety regulations. Replace the Lancing Device Cap. Other Info •Use only XPRESSGLUCO+ Control Solution with your XPRESSGLUCO+ meter. •Check the expiration date on the bottle. Do not use if expired. •Use within a period of 90 days from the date that you first open it. Record the discard date on the control solution bottle when you first open it to serve as a reminder to discard after 90 days. •The control solution ranges are printed on the label of the XPRESSGLUCO+ Blood Glucose Test Strip vial. They are not recommended target ranges for your blood glucose. •For in vitro diagnostic use. •Do not add any liquid to the XPRESSGLUCO+ Control Solution. •Do not take internally or inject.

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Clinical Chemistry

Infinite Liquid a-Amylase 12 ml Diagnostic Reagent from Accurex (Pack Size : 6 x 2 ml). a-Amylase reagent is used for determination of amylase activity based on kinetic method using Gal G2 – a CNP. Amylase is a ready-to-use reagent. Normal amylase level is 40 to 140 units per liter (U/L) or 0.38 to 1.42 microkat/L (µkat/L). Infinite a-Amylase can be used on any Spectrophotometer, Discrete semiautomated & Automated analyzers. Reaction type is Kinetic. Accurex Biomedical is the first biochemical reagents manufacturing company in India About Infinite a-Amylase ‘is a reagent set for determination of amylase activity based on kinetic method using Gal G2 – a CNP. Infinite a-Amylase is a ready-to-use reagent. Infinite a-Amylase can be determined in just 21/2 minutes at 37°C. Infinite a-Amylase is linear upto 2000 IU/1. Infinite a-Amylase is a High Stability Reagent. Infinite a-Amylase can be used on any Spectrophotometer, Discrete semiautomated and Automated analyzers. Programme can be designed for any specific analyzer upon request. Pack Size : 6 x 2 ml Principle Amylase test involves use of a chromogenic substrate Gal G, – a CNP (2-chloro-4-nitrophenyl linked with galactosyl maltoside). The direct action of amylase with this substrate results in the release of more than 90% of 2-chloro-4-nitrophenol, which can be monitored by kinetic assay at 405 nm. The increase in absorbance is directly proportional to the amylase activity in the sample. Quality Control To ensure adequate quality control, it is recommended that each batch should include a normal and abnormal commercial reference control serum. It should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect the performance of this test include proper instrument function, temperature control, cleanliness of glassware and accuracy of pipetting. Other Details Mix thoroughly and transfer the assay mixture immediately to the thermostated cuvette and start the stopwatch simultaneously. Record the first reading at 60 second and subsequently three more readings with 30 seconds interval at 405 nm.

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Clinical Chemistry

Autozyme Alkaline Phosphatase 60 Diagnostic Reagent (Pack Size : 12 x 5 ml) from Accurex. Alkaline Phosphatase 60 are used in the diagnosis of hepatobiliary disorders and bone disease associated with increased osteoblastic activity. Alkaline Phosphatase high levels may be a sign of a liver problem or a bone disorder Alkaline Phosphatase 60 reagent is set for determination of Alkaline Phosphatase activity based on kinetic method using p-nitrophenyl phosphate (p-NPP), the reagent is a Highly stable reagent & its activity can be determined in just 2.5 minutes. About Autozyme Alkaline Phosphatase is a reagent set for determination of Alkaline Phosphatase activity based on kinetic method using p-nitrophenyl phosphate (p-NPP) Autozyme Alkaline Phosphatase is a single reagent system using one step procedure Autozyme Alkaline Phosphatase has one step reconstitution. It involves dissolving substrate tablet in diluent Autozyme Alkaline Phosphatase is a Highly stable reagent Autozyme Alkaline Phosphatase activity can be determined in just 2.5 minutes Pack Size : 12 x 5 ml Principle The working solution is stablə for 21 days at 2- 8°C. The working solution should be prepared and stored in the dark (working solution bottle) provided.This is critical because the reagent is light sensitive. It should therefore be kept away from direct light. Alkaline Phosphatase cleaves p-nitrophenyl phosphate (p-NPP) into p-nitrophenol and phosphate. p-nitrophenol is a yellow color compound in alkaline medium and absorbs light at 405 nm. The rate of increase in absorbance at 405 nm. is proportional to Alkaline phosphatase activity in specimen. Quality Control To ensure adequate quality control, it is recommended that each batch should include normal and abnormal commercial reference control serum. It should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect the performance of this test include proper instrument function, temperature control, cleanliness of glassware and accuracy of pipetting. Other Details The kit should be stored at 2-8°C and is stable till the expiry date indicated on the label. The working solutions of Non Prostatic Acid Phosphatase & Total Acid Phosphatases are stable for 7 days at 2-8°C.

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Clinical Chemistry

Autozyme Alkaline Phosphatase 300 Diagnostic Reagent from Accurex (Pack Size : 30 x 10 ml). Alkaline Phosphatase reagent is used for determination of Alkaline Phosphate activity based on kinetic method using p-nitrophenyl phosphate (p-NPP). Alkaline Phosphatase is a single reagent system using one step procedure & Alkaline Phosphatase activity can be determined in just 2.5 minutes & is is a Highly stable reagent. Alkaline Phosphatase cleaves p-nitrophenyl phosphate p- NPP in the presence of magnesium ions to form p nitrophenol & phosphate. About Method – p-NPP-DEA Buffer – Kinetic reaction with 60 seconds lag phase – Easy reconstitution : Tablet + Diluent – High liquid stability : 21 days Autozyme Alkaline Phosphatase is a reagent set for determination of Alkaline Phosphate activity based on kinetic method using p-nitrophenyl phosphate (p-NPP) Autozyme Alkaline Phosphatase is a single reagent system using one step procedure Autozyme Alkaline Phosphatase has one step reconstitution. It involves dissolving substrate tablet in diluent Autozyme Alkaline Phosphatase is a Highly stable reagent Autozyme Alkaline Phosphatase activity can be determined in just 2.5 minutes Principle Alkaline Phosphatase cleaves p-nitrophenyl phosphate p- NPP) in the presence of magnesium ions to form p nitrophenol and phosphate. The intensity of the yellow color formed is directly proportional to the Application alkaline phosphatase activity in the specimen and measured kinetically. Quality Control To ensure adequate quality control, it is recommended that each batch should include normal and an abnormal commercial reference control serum. It should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect the performance of this test include proper instrument function, temperature control, cleanliness of glassware and accuracy of pipetting. Other Details Two liquid reagent systems. Stable till the expiry date indicated on the label when stored in 2-8°C.

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Clinical Chemistry

utozyme Albumin 300 Diagnostic Reagent from Accurex. Albumin 300 is used for determination of albumin in serum or plasma based on BCG method. Autozyme Albumin is a single reagent system which is ready to use, Albumin is linear up to 6 gm% & can be determined in 1 minute at room temperature. Serum albumin in the presence of Bromocresol-green under acidic condition forms a green coloured complex. Albumin normal range is 3.4 to 5.4 g/dL (34 to 54 g/L). About Autozyme Albumin is a reagent set for determination of albumin in serum or plasma based on BCG method Autozyme Albumin is a single reagent system, ready to use. Autozyme Albumin is linear up to 6 gm% Albumin can be determined in 1 minute at room temperature The shelf-life of Autozyme Albumin is 18 months Pack Size : 2 x 50 ml Principle Serum albumin in the presence of Bromocresol-green under acidic condition forms a green coloured complex, The absorbance of this complex is proportional to the albumin concentration in serum or plasma. Quality Control To ensure adequate quality control, it is recommended that each batch should include a normal and an abnormal commercial reference control serum,. it should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect the performance of this test include proper instrument function, cleanliness of glassware and accuracy of pipetting. Other Details The reagents are for in vitro diagnostic use. BCG reagent and standard should be stored at temperature indicated on the bottle label.

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Clinical Chemistry

Infinite ADA 60 Diagnostic Reagent (R1 1 X 20ml: R2 1 X 10 ml) from Accurex. Infinite ADA reagent is used for direct quantitative determination of Adenosine deaminase (ADA) activity in human serum, plasma and other body fluids. The Reagent is a ready-to-use two liquid reagent system & can be performed in 11 minutes at 37° C. ADA is also know as Adenosine Deaminase which eliminates a molecule called deoxyadenosine, which is generated when DNA is broken down. About Infinite ADA is a reagent set for direct quantitative determination of Adenosine deaminase (ADA) activity in human serum, plasma and other body fluids. Infinite ADA is a ready-to-use, two liquid reagent system. With Infinite ADA, the assay is linear upto 200 U/L. Infinite ADA assay can be performed in 11 minutes at 37° C. Principle ADA catalyzes deamination of adenosine to inosine which is then converted to hypoxanthine by purine nucleoside phosphorylase (PNP). Hypoxanthine is then converted to uric acid and hydrogen peroxide (H2O2) by xanthine oxidase (XOD). H2O2 is further reacted with N-Ethyl-N-(2-hydroxy-3- sulfopropyl)-3-methylaniline (EHSPT) and 4-aminoantipyrine (4 AAP) in the presence of peroxidase (POD) to generate quinone dye. Quality Control To ensure adequate quality control, it is recommended that each laboratory should use a normal and an abnormal commercial reference control material. It should be realized that the use of quality control material checks both reagent and instrument functions together. Factors which might affect the performance of this test include instrument function, temperature control, cleanliness of glasswares and accuracy of pipetting. Other Details The reagents R1 & R2 are ready-to-use. The reagent kit should be stored at 2° – 8° C and is stable till the expiry date indicated on the label. Reagent R1 is light-sensitive & to be stored in dark. Contamination of the reagents should be strictly avoided.

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Clinical Chemistry

Acid Phosphatase Diagnostic Reagent (Pack size: 8 x 1 ml) from Accurex. Acid Phosphatase is used in accordance with ISO 14189 to detect acid phosphatase from Clostridium perfringens. Autozyme Acid Phosphate reagent is set for determination of Acid Phosphatase activity based on Kinetic method using a-naphthyl phosphate. In acidic pH of the buffer system, the reagent hydrolyses a-naphthyl phosphate to a-naphthol & phosphate. Accurex has gained considerable expertise in manufacturing & marketing of In-vitro Diagnostic reagents. About Autozyme Acid Phosphate is a reagent set for determination of Acid Phosphatase activity based on Kinetic method using a-naphthyl phosphate Autozyme Acid Phosphate is a single reagent system using one step procedure Autozyme Acid Phosphate can be determined in just 8 minutes at 37 degree C Acid Phosphate can be used on any Spectrophotometer, Discrete semi automated and Automated Analyzer. Programme can be designed for any specific analyzer upon request. Pack Size : 8 x 1 ml Principle In acidic pH of the buffer system, Acid Phosphatase hydrolyses a-naphthyl phosphate to a-naphthol and phosphate. The o-naphthol is then coupled with Diazotized Fast Red TR to form a Diazo dye which has strong absorbance at 405 nm. The increase in absorbance is directly proportional to the level of acid phosphatase in serum. The addition of L-Tartrate inhibits prostatic acid phosphatase but does not inhibit other isoenzymes. The activity of Prostatic Acid Phosphatase is obtained by subtracting the result of Non prostatic Acid phosphatase (Determination with Tartrate) from Total Acid Phosphatase (without tartrate). Quality Control To ensure adequate quality control it is recommended that each batch should include a normal and an abnormal commercial reference control serum. It should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect ne performance of this test includes proper instrument function, temperature control, cleanliness of glassware and accuracy of pipetting.

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