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Clinical Chemistry

ADVIA 2400 Chemistry System The right balance of speed and efficiency The ADVIA® 2400 Clinical Chemistry System manages the most demanding workloads and meets high turnaround-time (TAT) goals. Its menu includes methods for testing drugs-of-abuse, therapeutic drugs (TDM) and new assays such as cystatin C and CardioPhase® hsCRP. The ADVIA 2400 Clinical Chemistry System offers: High throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage heavy workloads Rapid, consistent, 2-second cycle time for faster tube speed and test throughput User-defined automatic repeat, dilution, and reflex testing Large onboard reagent capacity and optional concentrated reagents help to minimize intervention demands Refrigerated onboard storage of controls and reagents for extended stability and increased productivity Automation-ready design: no additional hardware required Features & Benefits The ADVIA 2400 Clinical Chemistry System meets today’s high turnaround-time goals with a throughput of up to 2400 tests/hour. In addition to assays for general and specialty chemistries, its menu includes assays for specific protein measurement, drugs-of-abuse testing (DAT), and therapeutic drug monitoring (TDM). Interesting new assays such as cystatin C, HbA1c with automated sample pretreatment, and CardioPhase® hsCRP can now be included in your routine testing. The ADVIA 2400 Chemistry System pushes productivity levels while maintaining the reliability and stability that keep laboratories up and running. A rapid, 2-second probe cycle time maximizes tube speed and test throughput and combines with the system’s efficient automation-readiness to provide the turnaround time needed for high-volume laboratories Superior Speed and Productivity Throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage the heaviest workloads Rapid, consistent, 2-second cycle time Throughput of 200 tubes per hour, even when running three ISE tests and nine photometric tests per sample Automatic Sample Retain technology, auto-repeat, auto-dilution, and auto-reflex testing Automation-ready Point-in-space aspiration enables connectivity to a track. Redundant sample loading provides built-in backup and easy handling of non-routine samples. Direct sampling from track prevents tubes being detained at an analyzer and reduces aliquoting. Minimal Need for Operator Intervention Minimal-maintenance ISEs Large onboard reagent capacity and optional concentrated reagents for fewer interruptions No-maintenance, 37°C incubation oil bath Auto-calibration and auto-QC from refrigerated onboard calibrators and controls Microvolume technology with 32,000 tests onboard and up to 60 days' onboard stability for improved walkaway time. Concentrated reagents for increased maximum capacity. Remote diagnostics and Inter-Laboratory Quality Control (ILQC) options Exceptional Reliability Sample integrity check for icterus, hemolysis, and lipemia Sample probe with automatic clot/clog detection, liquid-level sensing, short-sample detection, and crash protection Advances in onboard reagent stability, calibration frequency, reduction in interferences, and expanded assay linearity

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Clinical Chemistry

ADVIA Chemistry XPT System An advanced, automated clinical chemistry analyzer for high-volume laboratories The ADVIA® Chemistry XPT System provides timely, reliable results with continuous operation to meet the chemistry workloads of the most demanding laboratories. Delivers high throughput of up to 2400 tests per hour. Manages comprehensive testing with a menu of more than 115 assays. Improves workflow using automation and system technologies such as micro-volume and aliquot retention. Features & Benefits The ADVIA Chemistry XPT System*** is engineered for continuous operation and timely, accurate results—supporting you to reach your full potential today and be prepared for tomorrow. With an advanced user interface that is easy to use and VeriSmart Technology to support accuracy of testing, the ADVIA Chemistry XPT System predictably and consistently delivers timely, reliable results to meet expanding workloads. Simplified, Continuous Operation Simplify operation and training with the intuitive, icon-driven user interface. Extend walkaway times with concentrated reagents that provide high test capacity onboard. Quickly load most system fluids on the fly. Automate calibration, QC, startup, and shutdown. Consistent, Predictable Turnaround Time and Accuracy Offer a comprehensive chemistry menu of over 115 assays, including general and specialty chemistry, DAT, TDM, and specific proteins. Push productivity with a throughput of up to 2400 tests per hour (1800 photometric, plus 600 ISE). Control testing: STAT and specialty samples can always be front-loaded while an automation track is running. Designed for Automation Adapt and grow with direct connectivity to Siemens Healthineers and . Simplify your laboratory operations with connectivity to IT solutions including , , and . Increase productivity and efficiency with direct-from-track sampling and onboard aliquoting that allows samples to be immediately released to the next workstation. Do More with Less Reduce blood-draw requirements with micro-volume technology that uses a single 30 μL sample for up to 15 tests. Eliminate sample callback with automated, pre-programmable dilution, reflex, and rerun testing that uses an onboard aliquot. Improve workflow and accuracy with VeriSmart echnologies that perform hardware and software checks at all stages of sample processing.

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Hematology

n large laboratories, rows of instruments are seen working tirelessly like miniature factories – only they produce not commodities but medical test results. Mindray CAL 8000 new-generation cellular automation line is one of them, but unlike a typical workhorse, it is intelligent. It is a highly automated workstation for smarter, faster, and more accurate cellular analysis. It can perform competently in the face of these challenges. The workstation can hold up to four units of BC-6800 automated hematology analyzer, which utilizes the advanced SF Cube technology and 3-D scatter grams to help doctors better differentiate blood cell populations and reveal abnormal cells undetectable by conventional techniques. With 125 CBC tests per hour per unit, BC-6800 brings the process rate of the workstation to 20–30 percent higher than other similar models, effectively alleviating laboratory's stress during the peak processing hours. On CAL 8000, the hematology analyzer, slide maker and stainer, CRP analyzer, and HbA1c analyzer are all integrated into one seamless production line through automated track modules and trolley. Simply by loading a single tube of blood sample onto the automation system, one can get all the test results. This innovative walk-away automation functionality has made possible the CBC+CRP+HbA1c testing all in one streamlined workstation for the first time in the industry. It offers a smart solution, or rather, a smart expert – the labX pert 2.0. It is a software that can automatically sort out the suspected samples for manual validation. The pathologist then decides if rerun or microscopic review is warranted based on their clinical experience. It avoids wasting slides and reduces extra work. Moreover, the onboard automated re-exam functionality also helps enhance work efficiency. The CMU software The touch screen is the “brain” of CAL 8000. It optimizes the distribution of workload between each analyzer unit and decides which sample requires a blood smear. It displays the status of each analyzer or SC-120 installed on CAL 8000 as well as the volume of balance reagent. This intuitive software can tell the users all necessary information of CAL 8000 at any given time. Consequently, the users spend less time operating CAL 8000 and can arrange their working schedule better. Multi “R” tests The CAL 8000 can automatically distribute the samples with “Repeat”, “Rerun” and “Reflex” criteria which are pre-defined by users.The re-exam criteria on CAL 8000 can be defined by many conditions, such as time, patient’s age, gender, department, etc. This helps minimize the number of blood smears. Special tube racks The special tube racks utilize different barcodes to differentiate specific testing purposes, such as “QC”, “Slide making & staining only” and “RET test only”. The special tube racks can carry the tubes to perform these specific functions in the simplest way.

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Instruments

CLIAlyzer is an intuitive bench-top chemiluminescent analyzer allowing for quick operation and use. CLIAlyzer delivers results when paired with our RapidLight tests. Laboratories can run multiple specimen options and six tests simultaneously, providing up to 24 test results per hour. The CLIAlyzer is an in vitro diagnostic device used for the quantitative determination of concentrations of various analytes found in serum, whole blood, or plasma specimens. Compact size Automated walkaway system Easy operation with 7-inch touchscreen Barcode reader reduces manual entry errors Results on screen, on a printout, or uploaded to database Storage capacity of 100,000 test results Laboratory Information System (LIS) connectivity High accuracy and precision with highly sensitive PMT for signal detection Assay results as quick as 15 minutes (test-specific) Compatibility with whole blood, serum, plasma (test-specific) Six cartridge positions Automatic detection of test parameter through barcode on test strip, thus reducing any user-related errors Low maintenance analyzer due to no storage of buffer System: Automated chemiluminescence system Interface: 7-inch color touch screen Methodology: Magnetic particle-based assay with chemiluminescence detection Reaction mode: Batch mode Sample type: Serum, plasma, whole blood (test specific) Sample positions: 6 Volume: 420mm x 610mm x 321mm Weight: 35kg Connectivity: USB, RS232, LIS connection Barcode Scanner: 1-D & 2-D barcode

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Immunology Analyzer

Fully Automated Chemiluminescence Immunoassay Analyzer Introducing iFlash 1200, a chemiluminescence immunoassay analyzer that offers fully automated immunoassay analysis using Magnetic particle-based Direct Chemiluminescence technology. With a high throughput of up to 120 tests per hour and a first result available in just 13 minutes, iFlash 1200 is one of the fastest and most efficient immunoassay analyzers available on the market. The instrument features continuous STAT sample loading capacity with 16 sample positions, continuous reagents loading capacity with 15 reagent positions, and continuous loading of reaction vessels with a capacity of 500 cuvettes. Additionally, iFlash 1200 uses Acridinium Ester Labeled Direct Chemiluminescence for highly accurate and reliable results, and comes with ready-to-use reagents in convenient 2 x 50 tests pack size for simplified testing. Overall, iFlash 1200 is an innovative and versatile immunoassay analyzer that is perfect for laboratories that require high throughput and rapid turnaround times. iFlash 1200 chemiluminescence immunoassay analyzer Key Features: 1.Continuous loading of reagents with convenient pack size of 2 x 50 tests 2.Continous loading of 500 reaction cuvettes for longer walkaway time 3. 4 step magnetic separation for achieving high precision and quality results 4.Non contact vortex mixer-Highly Efficient technology to prevent carryover & cross contamination Additional information General Information Throughput : upto 120 tests/hour Time to First Results :13 minutes Detection Principle Magnetic particle Based Direct Chemiluminescence Chemiluminescence Label :Acridinium Ester Sample System Sample Position :16 sample position Types of Sample tube :Microcup & blood collecting tubes Sample Volume :5~150μL Reagent System Reagent Position :15 reagent positions with onboard refrigeration Reagent Carousel Temp :2-8 °C Reagent Detection :Reagent Level Tracking Reagent Pack : 2 x 50 tests Reagent Carousel Incubation Capacity :48 reaction vessels Incubation Temperature :37°C+-0.3°C Mixing System :Non-Contact Vortex Mixer Operating Conditions Power Supply :100~240V, 50/60HZ Power Consumption :600VA Temperature :10~30°C Weight :120 Kg Reagents iFlash 1200 reagents iFlash 1200 reagents Pack size 2 x 50 Tests 28 days On board reagent stability 28 days Calibration stability Built in Calibrators for all Parameters

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Urinalysis

Product Description: This is a continuous loading system for automatic movement, timing, measurement & evaluation of urine test strips. Product Features: High Throughput - High Memory Capacity Easy operation via touchscreen Product Application: Automated reading of Urine test strips that avoids subjective errors in visual reading Technical Specifications: System: Continuous loading Semi-automated Urine test strip analyzer Type: Reflectance photometer Measuring System: Wavelengths – 460 nm, 530 nm, 610 nm Memory: 1000 results Throughput: 400 tests /hr User interface: LCD touchscreen (800 x 480 pixel) Printer: Built-in Thermal Printer Certificates: CE Physical Dimensions: 300 x 287 x 148 mm Weight : 3.2 Kg Test Strips: DekaPHAN Laura & MicroalbuPHAN Laura Parameters: Specific Gravity, Leucocytes, Nitrite, pH, Protein, Glucose, Ketone, Urobilinogen, Bilirubin, Blood & Microalbumin, Creatinine Optical QC: Grey QC strip System Interface: Communication via RS232 & USB port Host Protocol: Uni-directional Sample Identification: Sample ID via keyboard entry, barcode reader Power source: AC 100-240V/50-60 Hz Power consumption: ≤45 W

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Clinical Chemistry

Product Description: XL-640 with CRS is a random access, discrete, patient prioritized, fully automated clinical chemistry analyzer with autoloader designed to meet the needs of today’s modern clinical laboratories with high workload. Once samples are loaded, it is a complete walk-away system. XL 640 CRS is designed to operate smoothly over the long haul and to deliver consistent quality report. Product Features: Throughput of 400 tests/ hour (Photometric) and 640 tests/hour with ISE 56 Reagent Positions with On-board cooling for reagents 162 Sample positions with /Autoloader Separate probes for reagent R1 & R2 and dedicated probe for sample Clot detection for sample probe, Reflex testing and Serum Indices identification 72 permanent hard glass cuvettes with On-board Laundry Automatic dilution for high abnormal samples & Auto Rerun facility Extensive QC Programmes with Levy –Jennings Curve & QC rules. Automatic calculation for Mean SD & CV% Direct loading for primary tubes Touch screen User Friendly GUI with Bi-directional connectivity. System General System Type: Automated, Discrete, Random Access, Patient Prioritized Clinical Chemistry Analyzer with Autoloader Throughput: 400 photometric tests/hour & 640 tests/hour with ISE (*optional ISE with Na, K, Cl, Li) Analytical Methods: 1-Point, 2-Point, Rate-A, Rate-B, Direct Potentiometry(optional) Barcode Reader: Both for Samples & Reagents (Optional) Reactions Tray: 72 hard glass cuvettes Reaction Mixing: Dual Stirrer with variable speed Reading Volume: 180 µl On-Board Laundry: 6 stage cleaning, 2 stage drying Photometer: Multi-wavelength diffraction grating with 12 wavelengths (340, 376, 415, 450, 480, 505, 546, 570, 600, 660, 700 & 750 nm) O.D. Range: 0 - 3.0 Light Source: Halogen Lamp Detector: Silicon Photodiodes Water Consumption: < 14 liters/hour Programmable Parameters: Default system pack parameters + upto 99 user defined parameters, Unlimited profiles and unlimited calculation items Quality Control: Q.C. plot data with Q.C. Rules. Provision for lab mean. Twin plot. Caliberation: K- factor, Linear (1,2 point and multipoint) 4P and 5P Logit-log, Cubic spline,exponential, polynomial. On-board serial dilution for calibrator Power Requirement: AC 220 V ± 10 %, 50 Hz or AC 110 V ± 10 %, 60 Hz Power Consumption: 800 VA Dimensions: Approximately 897 mm (w) x 655 mm (D) x 1170 mm (H) Weight: Approximately 200 Kg Sample Handling Sample: Serum, Plasma, Urine, CSF, Whole blood, other Sample Unit: upto 162 positions for samples/STAT/calibrator/controls with Autoloader Sample Pipetting: 2-70 µl (adjustable in 0.1 µl steps) for biochemistry,70 µl fixed for ISE capacitance probe with liquid level sensing and vertical obstruction detection , clot detection and serum indices and Reflex Testing Auto Rerun: Repeat with same, increade and decresaed volume (upto 1:150) Sample Tubes/Cups: Primary tubes of 5 ml, 7ml and 10 ml and sample cups Reagent Handling Reagent Tray: 56 positions for reagents with on-board cooling Reagent Pipetting: R1: 60 - 300 µl (Adjustable in 1 µl step) R2: 0 or 10 - 300 l (Adjustable in 1 µl step) Capacitance probe with level sensing and vertical obstruction detection System Interface Analyzer-PC: USB PC- HOST Computer: Bidirectional TCP/IP and RS - 232 PC- Printer: USB Operating System: Windows based with Touch Screen User Friendly GUI Database: Unlimited Results

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Clinical Chemistry

XL 1000 with the throughput of upto 1040 tests per hour is the ideal instrument for centralizing the complete biochemistry testing load on a single fully automated platform. Increased walk away productivity and less human intervention make it an ideal analyzer for large laboratories. Equipped with all necessary advanced features that one expects from a high end fully automated chemistry analyzer; sample loading through rack system, cooled calibrator and control carousel, low reading volume of 150 µL, diffraction grating with 15 wavelengths from 340 nm to 800 nm and user-friendly software, to optimize and reliably run the daily lab workload. XL 1000 is a "dream come true" workhorse for laboratories with increased workload and the perfect solution. Fully Automatic, Discrete, Patient prioritized, Random Access Clinical Chemistry Analyzer with throughput of 1040 tests/hour 3 Reagent capabilities 147 long life Hard Glass cuvettes Separate Carousel for STAT samples Onboard refrigeration for reagents Extensive database for storing patient data and Q.C. results Primary tube sampling with bar code identification 9 stage laundry for cuvettes wash 150 samples can be loaded at a time through rack system System Discrete, open, automated, random access, patient prioritized, 1/2/3 reagent system DISPENSING OF SAMPLES AND REAGENTS Sample volume: 2-60 µl (0.1 µl step), 70 µl with ISE Reagent volume: 120 µl – 550 µl 3 dispensing probes ( R1, R2/R3) equipped with liquid -level sensor and crash detector Auto-dilution of samples and calibrators Clot detection Samples Serum, urine, plasma, CSF and other Economy Minimum reaction volume: 180 µl Reusable reaction cuvettes Mixing System 2 independent stirrers 3 user selectable mixing speeds Quality Control 4 levels of control material can be used Levey-Jennigs graphs Twin Plot diagrams for monitoring of systematic and random error Reaction unit with wash station 147 reusable hard glass cuvettes Possibility of replacement of individual cuvette Wash station – cuvette rinsing and drying in nine-step procedure Automatic cuvette blank measurement before analysis Sample Autoloader 23 racks 115 sample positions on automatic autoloader Primary tubes 5, 7 and 10 ml, vacuum system tubes Barcode reader for sample identification 2 Reagent trays With 43 cooled position each Barcode reader for reagent identification 20 ml, 50 ml reagent containers, 5 ml tube with adaptor Option to use one reagent for several test simultaneously Stat Tray 45 positions Can be used for blank, controls, STAT samples Software Convenient user interface Connection to LIS Programmable auto-start from sleep mode including automatic daily maintenance Statistical methods of processing results Data export in selected format Measurement Monitoring Colour indication of sample analysis Possibility of monitoring the reaction in real time Reagent volume monitoring Informative reports on ongoing analyzer status

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