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Clinical Chemistry

ADVIA 2400 Chemistry System The right balance of speed and efficiency The ADVIA® 2400 Clinical Chemistry System manages the most demanding workloads and meets high turnaround-time (TAT) goals. Its menu includes methods for testing drugs-of-abuse, therapeutic drugs (TDM) and new assays such as cystatin C and CardioPhase® hsCRP. The ADVIA 2400 Clinical Chemistry System offers: High throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage heavy workloads Rapid, consistent, 2-second cycle time for faster tube speed and test throughput User-defined automatic repeat, dilution, and reflex testing Large onboard reagent capacity and optional concentrated reagents help to minimize intervention demands Refrigerated onboard storage of controls and reagents for extended stability and increased productivity Automation-ready design: no additional hardware required Features & Benefits The ADVIA 2400 Clinical Chemistry System meets today’s high turnaround-time goals with a throughput of up to 2400 tests/hour. In addition to assays for general and specialty chemistries, its menu includes assays for specific protein measurement, drugs-of-abuse testing (DAT), and therapeutic drug monitoring (TDM). Interesting new assays such as cystatin C, HbA1c with automated sample pretreatment, and CardioPhase® hsCRP can now be included in your routine testing. The ADVIA 2400 Chemistry System pushes productivity levels while maintaining the reliability and stability that keep laboratories up and running. A rapid, 2-second probe cycle time maximizes tube speed and test throughput and combines with the system’s efficient automation-readiness to provide the turnaround time needed for high-volume laboratories Superior Speed and Productivity Throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage the heaviest workloads Rapid, consistent, 2-second cycle time Throughput of 200 tubes per hour, even when running three ISE tests and nine photometric tests per sample Automatic Sample Retain technology, auto-repeat, auto-dilution, and auto-reflex testing Automation-ready Point-in-space aspiration enables connectivity to a track. Redundant sample loading provides built-in backup and easy handling of non-routine samples. Direct sampling from track prevents tubes being detained at an analyzer and reduces aliquoting. Minimal Need for Operator Intervention Minimal-maintenance ISEs Large onboard reagent capacity and optional concentrated reagents for fewer interruptions No-maintenance, 37°C incubation oil bath Auto-calibration and auto-QC from refrigerated onboard calibrators and controls Microvolume technology with 32,000 tests onboard and up to 60 days' onboard stability for improved walkaway time. Concentrated reagents for increased maximum capacity. Remote diagnostics and Inter-Laboratory Quality Control (ILQC) options Exceptional Reliability Sample integrity check for icterus, hemolysis, and lipemia Sample probe with automatic clot/clog detection, liquid-level sensing, short-sample detection, and crash protection Advances in onboard reagent stability, calibration frequency, reduction in interferences, and expanded assay linearity

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Rapid Test

Buy AccuTest HIV – 1/2 Ab Rapid Card Test (50 Tests) Online from Accurex. This Rapid HIV test is a visual, solid phase immunochromatographic assay for qualitative in-vitro diagnostic detection of antibodies against HIV-1 and HIV-2 in human serum/plasma. This HIV test may be used as an aid in diagnosis of HIV infection. In the HIV blood test – A reactive result should be confirmed by supplemental testing as part of a validated HIV testing algorithm. INTENDED USE: AccuTest HIV – 1/2 Ab test is a visual, solid phase immunochromatographic assay for qualitative in-vitro diagnostic detection of antibodies against HIV-1 and HIV-2 in human serum/plasma. The product may be used as an aid in diagnosis of HIV infection. A reactive result should be confirmed by supplemental testing as part of a validated HIV testing algorithm. INTRODUCTION: The Human Immunodeficiency Virus (HIV) is a retrovirus that infects cells of the immune system, destroying or impairing their function. The most advanced stage of HIV infection is Acquired Immunodeficiency Syndrome (AIDS). The general method of detecting infection with HIV is to observe the presence of antibodies to the virus by an EIA method followed by confirmation with any confirmation method. AccuTest HIV – 1/2 Ab is a simple, visual qualitative test that detects antibodies in human serum/plasma. The test is based on immunochromatography and can give a result within 15 minutes. PRINCIPLE: AccuTest HIV – 1/2 Ab employs chromatographic lateral flow device in a cassette format. Colloidal gold conjugated recombinant antigens (Au-Ag) corresponding to HIV-1 (gp120 + gp41) and HIV-2 (gp-36) are dry-immobilized at the end of nitrocellulose membrane strip. HIV-1 & HIV-2 antigens are bound at the Test Zone (1 & 2) respectively. Goat Anti-Mouse IgG antibodies are bound at the Control Zone(C). When the sample is added, it migrates by capillary diffusion rehydrating the gold conjugate. If there are HIV-1 or HIV-2 antibodies in sample, they will bind with the gold conjugated antigens forming particles. These particles will continue to migrate along the strip until the Test Zone (1 or 2) where they are captured by the HIV-1 or HIV-2 antigens generating a visible purple line. If the specimen contains antibodies to HIV-1, the specimen will bind to the 1 test line and produce line. If specimen contains antibodies to HIV2, the specimen will bind to the 2 test line. If there are no HIV-1 or HIV-2 antibodies in sample, no purple line is formed in the Test Zone. The gold conjugate will continue to migrate alone until it is captured in the Control Zone (C) by the Goat Anti Mouse IgG antibodies aggregating in a purple line, which indicates that the migration of liquid has been successful. The control line must be present for the test to be valid. PRECAUTIONS: 1. For best results, adhere to instructions provided. 2. All specimens should be handled as potentially infectious. 3. The test device is sensitive to humidity as well as heat. 4. Do not use beyond expiration date. 5. Do not use test kit if pouch is damaged or seal is broken. 6. Use test device immediately after removing from the pouch. 7. The components (test device and assay diluents) in this kit have been quality control tested as a standard batch unit. Do not mix components from different lot numbers. 8. The AccuTest HIV – 1/2 Ab Test devices should be stored at 4 to 30 °C. Do not expose the kit to temperature over 30 °C. 9. Specimen with extremely high concentrations of red blood cells, fibrin should be recentrifuged before use. 10. AccuTest HIV – 1/2 Ab Test Device (Serum/Plasma) is for in vitro diagnostic use only. 11. AccuTest HIV – 1/2 Ab Test Device (Serum/Plasma) will only indicate the presence of antibodies to HIV-1/2 in the specimen and should not be used as the sole criteria for the diagnosis of HIV-1, HIV-2, and/or HIV-1 subtype O infection. 12. For confirmation of reactive test results, specimens should undergo further testing using different assays, such as rapid diagnostic tests, EIA and/or Western blotting in accordance with a validated HIV testing algorithm. 13. As with all diagnostic tests, all results must be interpreted together with other clinical information available to the physician. 14. Results should not be used to determine the serotype of HIV infections TEST PROCEDURE: 1. Allow the test device, buffer and specimen to reach room temperature (15-30 °C) prior to testing. 2. Remove the test device from the foil pouch and use the test device as soon as possible (within one hour). 3. Place the device on a flat, dry surface. Label with specimen ID. 4. Holding the sample dropper vertically above the test disk, slowly transfer 1 drop (10µl) of sample in to the sample well, then add 2 drops of assay diluent (about 75 µl) and start the timer. 5. As the test begins to work, you will see purple color moving across the result Window in the center of the Test Disk. 6. Wait for the colored lines to appear. Interpret test results at 15 to 20 minutes. Do not interpret test result after 20 minutes. STORAGE AND STABILITY Store as packaged in the sealed pouch at 4-30 °C (storage in refrigerator is permitted). Do not store in the freezer. Protect the test kit from humidly. The test device is stable until the expiration date printed on the test kit and/or sealed test device pouch. Do not use beyond the expiration date. The test device must remain in the sealed pouch until use.

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Clinical Chemistry

Infinite Liquid a-Amylase 12 ml Diagnostic Reagent from Accurex (Pack Size : 6 x 2 ml). a-Amylase reagent is used for determination of amylase activity based on kinetic method using Gal G2 – a CNP. Amylase is a ready-to-use reagent. Normal amylase level is 40 to 140 units per liter (U/L) or 0.38 to 1.42 microkat/L (µkat/L). Infinite a-Amylase can be used on any Spectrophotometer, Discrete semiautomated & Automated analyzers. Reaction type is Kinetic. Accurex Biomedical is the first biochemical reagents manufacturing company in India About Infinite a-Amylase ‘is a reagent set for determination of amylase activity based on kinetic method using Gal G2 – a CNP. Infinite a-Amylase is a ready-to-use reagent. Infinite a-Amylase can be determined in just 21/2 minutes at 37°C. Infinite a-Amylase is linear upto 2000 IU/1. Infinite a-Amylase is a High Stability Reagent. Infinite a-Amylase can be used on any Spectrophotometer, Discrete semiautomated and Automated analyzers. Programme can be designed for any specific analyzer upon request. Pack Size : 6 x 2 ml Principle Amylase test involves use of a chromogenic substrate Gal G, – a CNP (2-chloro-4-nitrophenyl linked with galactosyl maltoside). The direct action of amylase with this substrate results in the release of more than 90% of 2-chloro-4-nitrophenol, which can be monitored by kinetic assay at 405 nm. The increase in absorbance is directly proportional to the amylase activity in the sample. Quality Control To ensure adequate quality control, it is recommended that each batch should include a normal and abnormal commercial reference control serum. It should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect the performance of this test include proper instrument function, temperature control, cleanliness of glassware and accuracy of pipetting. Other Details Mix thoroughly and transfer the assay mixture immediately to the thermostated cuvette and start the stopwatch simultaneously. Record the first reading at 60 second and subsequently three more readings with 30 seconds interval at 405 nm.

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Clinical Chemistry

Autozyme Alkaline Phosphatase 300 Diagnostic Reagent from Accurex (Pack Size : 30 x 10 ml). Alkaline Phosphatase reagent is used for determination of Alkaline Phosphate activity based on kinetic method using p-nitrophenyl phosphate (p-NPP). Alkaline Phosphatase is a single reagent system using one step procedure & Alkaline Phosphatase activity can be determined in just 2.5 minutes & is is a Highly stable reagent. Alkaline Phosphatase cleaves p-nitrophenyl phosphate p- NPP in the presence of magnesium ions to form p nitrophenol & phosphate. About Method – p-NPP-DEA Buffer – Kinetic reaction with 60 seconds lag phase – Easy reconstitution : Tablet + Diluent – High liquid stability : 21 days Autozyme Alkaline Phosphatase is a reagent set for determination of Alkaline Phosphate activity based on kinetic method using p-nitrophenyl phosphate (p-NPP) Autozyme Alkaline Phosphatase is a single reagent system using one step procedure Autozyme Alkaline Phosphatase has one step reconstitution. It involves dissolving substrate tablet in diluent Autozyme Alkaline Phosphatase is a Highly stable reagent Autozyme Alkaline Phosphatase activity can be determined in just 2.5 minutes Principle Alkaline Phosphatase cleaves p-nitrophenyl phosphate p- NPP) in the presence of magnesium ions to form p nitrophenol and phosphate. The intensity of the yellow color formed is directly proportional to the Application alkaline phosphatase activity in the specimen and measured kinetically. Quality Control To ensure adequate quality control, it is recommended that each batch should include normal and an abnormal commercial reference control serum. It should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect the performance of this test include proper instrument function, temperature control, cleanliness of glassware and accuracy of pipetting. Other Details Two liquid reagent systems. Stable till the expiry date indicated on the label when stored in 2-8°C.

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Clinical Chemistry

As the workload and test menu increase, simultaneous management of multiple ELISA protocols can become challenging. The LisaXL has been designed with an open architecture to meet various laboratory needs, providing all the tools necessary for hands-free ELISA processing, increasing the reliability and reproducibility, improving throughput, and freeing the laboratory staff from repetitive steps. LisaXL allows running multiple parameters for over 250 samples in a single batch. Equipped with dual probes and dedicated workstations, drastically improve ELISA workflows. LisaXL is a complete walkway system that minimizes manual errors while improving the accuracy and turnaround time for critical tests. LisaXL provides the flexibility to build and run virtually any ELISA assays. Product Features: Lisa XL is a true walk-away system for any laboratory needs. High Throughput with 6 plates, can process up to 576 tests. A dynamic scheduler ensures optimized system usage and turnaround times by processing 6 plates and up to 12 assays in each plate Onboard flexibility with sample capacity up to 272 and 20 interchangeable racks for reagents and samples. Dual probe processing ensures speed and reliability. "Zero" carryover with high-quality disposable tips. Six individually controlled incubators and shakers with variable temperature, time, and speed settings. Efficient washing with super sweep mode ensures minimum residual volume, with up to 6 different wash buffers. Easy to use touchscreen graphic user interface Product Applications: ELISA Physical Specifications 1 Dimensions Length 1375 mm 55" Height 845 mm 33" Width 850 mm 33.5" Weight 195 kgs (Approx) Power Supply Voltage 100 - 240 Volts Frequency 50 / 60Hz Power consumption 700 W General Specifications Assay per plate Up to 12 Number of ELISA plates Up to 6 Sample capacity Up to 272 Sample / Reagent capacity Total 20 racks Single rack holds 16 sample / reagent tubes Double rack holds 6 x 60 ml reagent bottles (can be used interchangeably) Tip / Dilution box Total 11 locations of 96 capacity each (can be used interchangeably) Reader Specifications Reading Range 0.0 - 3.5 O.D Reading Channels 8 Filter wheel 8 positions 405 nm, 450 nm, 492 nm, 620 nm std* 578 nm and 700 nm optional + 2 open Light source Halogen Lamp Reading mode Single, Dual, ORR Reading time < 1 min (for single filter) Linearity Up to 3.0 O.D (450 nm) Washer Specifications Manifold configuration 16 needles - 8 aspiration & 8 dispensing Precision < 5 % at 300 μl Wash cycle Programmable Residual volume < 5 μl / well Soak time Programmable Washer buffer capacity 6 × 2.25 L Waste water container 1 × 20 L Incubator Specifications Number of incubators Up to 6 Temperature range RT + 5°C up to 50°C Temperature stability ± 1°C Incubation time Programmable Time to set temperature < 6 min Shaking 200 to 800 RPM Shaking Method Orbital Pipetting Specifications Number of probes 2 Tips 300 µl / 1000 µl, Auto / Manual selected Multi-dispensing (Reagent) Minimum volume 4 μl Serum dispensing time < 14 min Reagent dispensing time < 5 min Sample mixing Yes (Automatic) Precision Sample & Reagent Sample Dispensing with 300 µl tip: 3% above 10 µl ± 0.5 µl for 10 µl & less Reagent Dispensing with 300 µl tip: 3% for 25 µl & above Reagent Dispensing with 1ml tip: 5% for 75 µl & above" Process Security Liquid level sensing Well fill verification Clot detection Onboard sample identification Onboard reagent identification Strip verification Buffer sensing Alarms Software Operating System Windows 10 (Embedded) LIS interface Bi-directional, Serial / TCPIP USB Port Graphic load interface Graphical work list Data processing Quantitative, Semi-Quantitative & Qualitative Multi password access Ability to archive data Computer (Base configuration considered, higher configuration can be considered for upgrade after testing) Intel Core i3, 4 GB RAM, 1 TB hard disk Monitor 22" Full HD touch screen

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Clinical Chemistry

EM 360 is a Fully Automated Clinical Chemistry Analyser which is time tested and proven technology. It is designed to provide the most demanding productivity, speed and operational ease. EM 360 with a throughput of 360 tests/hour offers flexibility in operation and rugged performance to win against high workload, tight deadlines, multiple tasks and complexity of testing. It yields high quality results for virtually any biochemistry test to deliver quick, efficient and consistent performance. Product Features: Automated, Discrete, Patient prioritized, Floor model Based on proven technology, Diffraction Grating Separate probes for Reagent R1 & R2 and dedicated probe for sample Low reading volume of 200 µl only Onboard cooling for reagents to enhance the reagent stability Barcode for reagents & samples (Optional) Wide test menu Product Applications: End Point Reactions: Glucose, Cholesterol, Triglycerides, Albumin, Total Protein, Uric Acid, Calcium, Magnesium, Bilirubin Total, Bilirubin Direct Kinetic Reactions: SGOT, SGPT, GGT, LDH, CK, CK MB, ALP, ACP, Amylase, Lipase Two Point Rate Reactions: Urea, Creatinine Immunoturbidimetric Chemistries: RA, CRP, ASO, Direct HDL, Direct LDL, Apo A, ApoB, Lp (a) Special Chemistries: HbA1c, Iron, Ferritin, Phosphorus, Microprotein, Ammonia, Bicarbonates System Type: Discrete, automated, random access, patient prioritized clinical chemistry analyzer Throughput: 360 tests / hour photometric and 600 tests / hour with ISE* (*optional ISE with Na+, K+, Cl-, Li+) Analytical Methods: 1-Point, 2-Point, Rate-A, Rate-B, Direct Potentiometry (optional) Barcode Reader: For reagents and samples (optional) Reaction Tray: 60 hard glass cuvettes Reaction Mixing: Stirrer with variable speed Minimum reaction Volume: 150 μl with maximum 200 μl reading volume On-board Laundry: 5 stage cleaning, 2 stage drying Photometer: Multi-wavelength diffraction grating with 12 wavelengths (340, 376, 415, 450, 480, 505, 546, 570, 600, 660, 700, 750 nm) OD Range: 0.0 - 3.0 Light Source: Halogen lamp Detector: Silicon photo-diode Water Consumption: < 10 litres Programmable Parameters: Default system pack parameters + upto 99 user defined parameters, Unlimited profile and unlimited calculation items Quality Control: QC plot data with QC rules. Provision for lab mean. Twin plot Calibration: K-Factor, Linear (1, 2 point & multipoint), 4P and 5P Logit-log, cubic spline, exponential, polynomial, On-board serial dilution for calibrator Power Requirement: AC 220 V ± 10 %, 50 Hz or AC 110 V ± 10 %, 60 Hz Power Consumption: 800 VA Dimension (mm): Approx. 675 (W) x 840 (D) x 1120 (H) Weight: Approx. 150 kgs. SAMPLE HANDLING Sample: Serum, Plasma, Urine, CSF, Whole blood, other Sample Unit: 82 positions for samples, blank , controls, calibrators, STAT sample Sample Pipetting: 2 - 70 µl (adjustable in 0.1 µl step) for Biochemistry, 70 µl fixed for ISE Capacitance probe with liquid level sensing & vertical obstruction detection, serum indices Auto Rerun: Repeat with same, increased or decreased volume ( upto 1:150) Sample Tubes /Cups: Primary tubes of 5 ml, 7 ml, 10 ml and sample cups REAGENT HANDLING Reagent Tray: 50 positions for reagents with onboard cooling Reagent Pipetting: R1: 50 - 300 µl (adjustable in 1 µl step) R2: 10 - 200 µl (adjustable in 1 µl step) Capacitance probe with level sensing & vertical obstruction detection SYSTEM INTERFACE: Analyzer-PC: USB PC - Host Computer: Bidirectional TCP / IP & RS - 232 PC - Printer: USB Operating System: Windows Based Database: Unlimited Results

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Clinical Chemistry

The ADVIA® 1800 Clinical Chemistry System pushes the limit of productivity. Its extensive menu allows integration of testing for clinical chemistry, drugs-of-abuse, therapeutic drug monitoring (TDM) and specific proteins such as cystatin C and CardioPhase® hsCRP. The ADVIA 1800 Clinical Chemistry System offers: Throughput of up to 1,800 tests per hour to keep pace with workload peaks 200 basic metabolic panels per hour to meet turnaround-time demands Large onboard reagent capacity and optional concentrated reagents to reduce interruptions Optimal standardization of reagents and systems for efficient consumable usage Refrigerated onboard storage of controls and reagents for extended stability and increased productivity Automation-ready design: no additional hardware required Features & Benefits The ADVIA 1800® Clinical Chemistry System pushes the limit of productivity in the core lab and meets the turnaround-time (TAT) goals of today’s laboratories. Its extensive menu allows integration of general clinical chemistry testing with testing for drugs-of-abuse, TDM, special chemistry, and specific proteins such as cystatin C and CardioPhase® hsCRP. Automation-ready design Point-in-space aspiration enables connectivity to a track, VersaCell® System. Redundant sample loading provides built-in backup and easy handling of non-routine samples. Direct sampling from track prevents tubes being detained at an analyzer and reduces aliquoting. Peak productivity Throughput of up to 1,800 tests per hour provides the speed to keep pace with workload peaks. Throughput of 200 basic metabolic panels per hour helps to meet turnaround-time demands. Automatic Sample Retain technology lets you perform reruns and dilutions without the need to retrieve primary tubes. Consolidate chemistry testing on one system with a comprehensive menu, consistent cycle times, speed, and open application capability. Total system reliability Minimal-maintenance ISEs Robust hardware and simplified software design, with automatic calibration validation and tracking Advances in reagent onboard stability, calibration frequency, interference reduction and assay linearity expansion Direct water connection Remote diagnostics and Inter-Laboratory Quality Control (ILQC) options Easy efficiency Large onboard reagent capacity and optional concentrated reagents reduce interruptions. High-resolution touchscreen delivers push-button operation. Reagent pause capability and onboard Sample Pause button make loading easy. Minimal maintenance requirements, including no-maintenance oil bath, reduce hands-on time. Sample integrity checking, include serum indices reporting, short-sample flagging, and clot detection, reducing the need for manual intervention.

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Clinical Chemistry

With the built-in oxygen concentration monitoring system and effective cable management system, the HyPort R80 is capable of creating a reliable and streamlined ICU environment to ensure patient safety. Recovery The lighting system of the HyPort R80 aims to create a comfortable, near-natural light ICU environment to enhance patient recovery. 1234 1 Circadian Light Simulating 24-hour natural daylight change to reflect circadian rhythm. 2 Examination Light Up to 10,000 lux, 5-level adjustable illuminance meets various needs of head and abdominal examination. 3 Reading Light Effectively avoid invalid glare to meet the reading needs of rehabilitating patients. 4 Navigation Light Providing enough lighting with less glare for medical staff’s easy observation and intervention. Efficiency The HyPort R80 is a highly integrated bedside device management system that helps caregivers organize medical devices to meet various clinical needs. It makes efficient use of beside space with a series of easy-to-use designs, enabling a more efficient workflow for medical staff. Folding-shelf design Suitable for both portable ventilators and integrated ventilators. p46-s3-2-web Bag-valve-mask management Making sure bag valve mask is easy to access and ready for emergency situations anytime when needed. p46-s3-3-web Partition management The pump separation layout allows medical staff to easily identify infusion pumps and feeding pumps. p46-s3-4-web Smooth movement The advanced braking technology ensures stability of the column when moving. NextPrevious Variety The HyPort R80 has been designed to meet the demands of different ICU layouts to create a safer, more efficient and comfortable ICU environment with patient-centric design.ICU double room solution A Product Specification Usage/Application Hospital Brand Mindray Model Name/Number HyPort B80 Features 60 Degreepanel interface for easier plug-in of gas and electricity Color White Panel Interface 60 Degree Product Description Gas and electricity separated 60°panel interface for easier plug-in of gas and electricity Flexible movement of sliding and rotating of the distributions Additional accessories for better management of details Considerate lighting option Safer and more effective workflow Gas and electricity separated 60°panel for easier plug-in of gas and electricity Better management Customized drawer solutions Wire basket - dfferent size options available Cable management solutions

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