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Clinical Chemistry

Best Fully Automated Clinical Chemistry Analyzer – Sphera M from Accurex. This chemistry analyzer is made in Italy & provides Accurate, Precise and Rapid Testing Solution. Sphera M is a Compact, fully automated, open random-access analyzer. The Minimum reaction volume is 210 µl, Minimal < 1L/h water consumption, 80 reusable UV transmitting Bionex® plastic cuvettes, 8-step wash station. It has Removable refrigerated tray with 30 open reagent positions for 50 ml or 20 ml bottles. Multiple virtual reagent disks can be programmed. The Chemistry analyser also does Auto-wash of inner & exterior probe surface. QUALITY CONTROL & CALIBRATION QUALITY CONTROL: • Levey-Jennings plots and Westgard multi rules • Upto 3 QC levels per test • QC monitor and reports • Method statistics: Test counter, CV%, mean, graphical trend analysis CALIBRATION: • Method and reagent monitor (volumes, available tests, calibration, QC status) • Automatic pre-dilution for calibrators • Upto 8 calibrators per method • Auto recalculation of result using last calibration. UNIQUE SOFTWARE DESIGN AND ARCHITECTURE: • Software designed for touch screen use • Intuitive user interface • Continuous loading of samples and reagents • Random-access and STAT • Free choice of execution order • Extended walk-away capability • Results archive with cumulative charts • Programmable automatic start up routine • Multiple work lists INTERFACE: • Bi-directional LIS, ASTM, over ethernet port of the external PC • Positive identification of samples with internal barcode reader (optional) • Printing on any Windows 7®/8® compatible printer • Method defined washing programs SYSTEM PACKS FOR SPHERA™ Accurex has developed dedicated system packs for Sphera™. Our biochemistry reagents have been intensively evaluated and validated to achieve the highest performance in Sphera™. Accurex recommends the use of these system packs according to instructions and applications validated by Accurex. Safety Information 8-step wash station for thorough cleaning of each cuvette (Needles: 6 dispensing, 6 aspiration, 1 cleaning) • Two types of systemic and special washing solutions for removing obstinate probe residues Direction for Use QUALITY CONTROL • Levey-Jennings plots and Westgard multi rules • Upto 3 QC levels per test • QC monitor and reports • Method statistics: Test counter, CV%, mean, graphical trend analysis CALIBRATION • Method and reagent monitor (volumes, available tests, calibration, QC status) • Automatic pre-dilution for calibrators • Upto 8 calibrators per method • Auto recalculation of result using last calibration Other Info Accurex has developed dedicated system packs for Sphera™. Our biochemistry reagents have been intensively evaluated and validated to achieve the highest performance in Sphera™. Accurex recommends the use of these system packs according to instructions and applications validated by Accurex.

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Clinical Chemistry

Product Specification Model Name/Number HumaStar 200 Brand Human Automation Fully Automatic Display Digital Dimensions 69 x 76 x 52 cm (WxDxH) Frequency 50/60 Hz Voltage 220-240 or 110-120 Vac Temperature 16-30 Degree C Throughput Up to 200 t/h throughput Weight 51 kg Reaction volume 210-350 il Wash station 6 dispensing needles Water consumption < 2 l/h (8 ml/test) Languages English, French, Spanish Software (other languages can be added) Humidity < 80 % non-condensing Data External computer required (Pentium IV, 2 GHz Mode Open, random-access, STAT Product Description Product Detail : Unique Random-Access Analyzers for Small to Medium Size Laboratories Unique design Unique software architecture Unique features Analysis Endpoint (bichromatic), Differential endpoint (with sample blank), Fixed time, Kinetic (bichromatic) Multi-standard (up to 8), factor, linear, non linear (cubic-spline, poly-linear and logit-log four parameters) Samples Removable sample tray 60 positions: primary tubes 12–12.5x100 mm and 10 mm cups Optional: sample tray for 20 primary tubes 12–16x100 mm and 20 cups 3.5 ml Sample volume: 2–300 µl Internal barcode reader Automatic pre- and post-dilution Test profiles and replicates Reagents Removable reagent tray 30 reagent / diluent positions 50 and 20 ml bottles, adapter for tubes and cups Reagent volumes: 5–350 µl Refrigeration to ~9 Degree C below ambient (at bottom of bottle) Substrates, Enzymatic, Turbidimetric Reaction Reaction volume: 210–350 µl 80 reusable Bionex® cuvettes 6 mm optical path Heat transfer by air Pipetting Needle shock detector Capacitive liquid level detector Wash station 8-step cuvette wash station Systemic and special washing solution HumaStar 200: 6 dispensing needles Water consumption < 2 l/h (8 ml/test) Optical system 9 discrete wavelengths (340, 405, 505, 546, 578, 600, 650, 700 nm, one free position) Band pass: +/– 5 nm Photometric linearity: 0–2.5 Abs Stability: <1 % drift per day Management 20 GB HDD, 512 MB RAM, CD/R, USB) Windows 7® with .NET framework 4.0 English, French, Spanish OS recommended Core i3TM or dedicated graphic card recommended Minimum 900 dots resolution Designed for touch screen (1280x1024 pixel) LIS: Bi-directional, polling mode, ASTM, ethernet Printouts By patient, single test, complete sample, work sheet, method and QCs, calibration curves, kinetics, continuous printing

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Immunology Analyzer

Product Description: Erba Lisa Wash II is a simple easy to Operate and use ELISA Plate Washer, Suitable for all ELISA applications. Programmable features like, dispense pressure, Single/double aspiration, Horizontal & Vertical adjustments ensures complete control on washing efficiency Product Features: Fully automated, easy operating system and friendly software with large-screen display 50 user programmable protocols to customize washing Easily removable 8- or 12-way manifolds Liquid level detection and alert function Low residual volume: <3 µl Soak time programmable up to 24 hrs. Compatible for flat-bottom, U and V bottom type microplates or microstrip High-efficiency ELISA washing with automated monitoring of Vacuum. Choice of 2 wash buffer bottles, 1 distilled water & 1 waste container with sensor Dispense pressure and the volume adjustable, so as to reduce the air bubbles and ensure thorough Washing Waste-bottle sensor to detect high-waste liquid levels Standard aerosol protection cover Easy maintenance CE marked Product Applications: ELISA Wash Head: 8 and 12 head manifold compatible Wash Mode: Row and Plate Wash Row: 1-12 rows Flat Bottom Plate Type: 96 or 48 well plate or strip (Flat, U & V - bottom) Wash Programs: 50 Moving Cycle: up to 12 cycles Dispensing Volume: 50 - 3000μl in 50μl increments Dispensing Precision: < 2% at 350μl Prime Volume: 50 - 1000μl Aspiration Pressure: Automatic Soak Time: 0 – 24 Hrs Residual Volume: ≤ 2μl for V/ U bottom plates, and ≤ 3μl for per well Flat bottom plates Nos. of Bottles: 2 wash, 1 Rinse/DI, 1 waste with level sensor, 2L each User Interface: 5 Inch LCD (90 x 53 mm), with Keypad Bottle Capacity: > 2 L Operating Environment Power Supply: AC 220 V/ 110 V, 50/60 Hz Input Power : < 80VA Operating Temperature: 10°C - 30°C Relative Humidity: Up to 95% relative humidity without condensation Storage Temperature: -10°C - 40°C Weight: 9.5 Kg Dimension: 710 mm x 530 mm x 380 mm

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Clinical Chemistry

As the workload and test menu increase, simultaneous management of multiple ELISA protocols can become challenging. The LisaXL has been designed with an open architecture to meet various laboratory needs, providing all the tools necessary for hands-free ELISA processing, increasing the reliability and reproducibility, improving throughput, and freeing the laboratory staff from repetitive steps. LisaXL allows running multiple parameters for over 250 samples in a single batch. Equipped with dual probes and dedicated workstations, drastically improve ELISA workflows. LisaXL is a complete walkway system that minimizes manual errors while improving the accuracy and turnaround time for critical tests. LisaXL provides the flexibility to build and run virtually any ELISA assays. Product Features: Lisa XL is a true walk-away system for any laboratory needs. High Throughput with 6 plates, can process up to 576 tests. A dynamic scheduler ensures optimized system usage and turnaround times by processing 6 plates and up to 12 assays in each plate Onboard flexibility with sample capacity up to 272 and 20 interchangeable racks for reagents and samples. Dual probe processing ensures speed and reliability. "Zero" carryover with high-quality disposable tips. Six individually controlled incubators and shakers with variable temperature, time, and speed settings. Efficient washing with super sweep mode ensures minimum residual volume, with up to 6 different wash buffers. Easy to use touchscreen graphic user interface Product Applications: ELISA Physical Specifications 1 Dimensions Length 1375 mm 55" Height 845 mm 33" Width 850 mm 33.5" Weight 195 kgs (Approx) Power Supply Voltage 100 - 240 Volts Frequency 50 / 60Hz Power consumption 700 W General Specifications Assay per plate Up to 12 Number of ELISA plates Up to 6 Sample capacity Up to 272 Sample / Reagent capacity Total 20 racks Single rack holds 16 sample / reagent tubes Double rack holds 6 x 60 ml reagent bottles (can be used interchangeably) Tip / Dilution box Total 11 locations of 96 capacity each (can be used interchangeably) Reader Specifications Reading Range 0.0 - 3.5 O.D Reading Channels 8 Filter wheel 8 positions 405 nm, 450 nm, 492 nm, 620 nm std* 578 nm and 700 nm optional + 2 open Light source Halogen Lamp Reading mode Single, Dual, ORR Reading time < 1 min (for single filter) Linearity Up to 3.0 O.D (450 nm) Washer Specifications Manifold configuration 16 needles - 8 aspiration & 8 dispensing Precision < 5 % at 300 μl Wash cycle Programmable Residual volume < 5 μl / well Soak time Programmable Washer buffer capacity 6 × 2.25 L Waste water container 1 × 20 L Incubator Specifications Number of incubators Up to 6 Temperature range RT + 5°C up to 50°C Temperature stability ± 1°C Incubation time Programmable Time to set temperature < 6 min Shaking 200 to 800 RPM Shaking Method Orbital Pipetting Specifications Number of probes 2 Tips 300 µl / 1000 µl, Auto / Manual selected Multi-dispensing (Reagent) Minimum volume 4 μl Serum dispensing time < 14 min Reagent dispensing time < 5 min Sample mixing Yes (Automatic) Precision Sample & Reagent Sample Dispensing with 300 µl tip: 3% above 10 µl ± 0.5 µl for 10 µl & less Reagent Dispensing with 300 µl tip: 3% for 25 µl & above Reagent Dispensing with 1ml tip: 5% for 75 µl & above" Process Security Liquid level sensing Well fill verification Clot detection Onboard sample identification Onboard reagent identification Strip verification Buffer sensing Alarms Software Operating System Windows 10 (Embedded) LIS interface Bi-directional, Serial / TCPIP USB Port Graphic load interface Graphical work list Data processing Quantitative, Semi-Quantitative & Qualitative Multi password access Ability to archive data Computer (Base configuration considered, higher configuration can be considered for upgrade after testing) Intel Core i3, 4 GB RAM, 1 TB hard disk Monitor 22" Full HD touch screen

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Clinical Chemistry

XL 1000 with the throughput of upto 1040 tests per hour is the ideal instrument for centralizing the complete biochemistry testing load on a single fully automated platform. Increased walk away productivity and less human intervention make it an ideal analyzer for large laboratories. Equipped with all necessary advanced features that one expects from a high end fully automated chemistry analyzer; sample loading through rack system, cooled calibrator and control carousel, low reading volume of 150 µL, diffraction grating with 15 wavelengths from 340 nm to 800 nm and user-friendly software, to optimize and reliably run the daily lab workload. XL 1000 is a "dream come true" workhorse for laboratories with increased workload and the perfect solution. Fully Automatic, Discrete, Patient prioritized, Random Access Clinical Chemistry Analyzer with throughput of 1040 tests/hour 3 Reagent capabilities 147 long life Hard Glass cuvettes Separate Carousel for STAT samples Onboard refrigeration for reagents Extensive database for storing patient data and Q.C. results Primary tube sampling with bar code identification 9 stage laundry for cuvettes wash 150 samples can be loaded at a time through rack system System Discrete, open, automated, random access, patient prioritized, 1/2/3 reagent system DISPENSING OF SAMPLES AND REAGENTS Sample volume: 2-60 µl (0.1 µl step), 70 µl with ISE Reagent volume: 120 µl – 550 µl 3 dispensing probes ( R1, R2/R3) equipped with liquid -level sensor and crash detector Auto-dilution of samples and calibrators Clot detection Samples Serum, urine, plasma, CSF and other Economy Minimum reaction volume: 180 µl Reusable reaction cuvettes Mixing System 2 independent stirrers 3 user selectable mixing speeds Quality Control 4 levels of control material can be used Levey-Jennigs graphs Twin Plot diagrams for monitoring of systematic and random error Reaction unit with wash station 147 reusable hard glass cuvettes Possibility of replacement of individual cuvette Wash station – cuvette rinsing and drying in nine-step procedure Automatic cuvette blank measurement before analysis Sample Autoloader 23 racks 115 sample positions on automatic autoloader Primary tubes 5, 7 and 10 ml, vacuum system tubes Barcode reader for sample identification 2 Reagent trays With 43 cooled position each Barcode reader for reagent identification 20 ml, 50 ml reagent containers, 5 ml tube with adaptor Option to use one reagent for several test simultaneously Stat Tray 45 positions Can be used for blank, controls, STAT samples Software Convenient user interface Connection to LIS Programmable auto-start from sleep mode including automatic daily maintenance Statistical methods of processing results Data export in selected format Measurement Monitoring Colour indication of sample analysis Possibility of monitoring the reaction in real time Reagent volume monitoring Informative reports on ongoing analyzer status

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Biochemistry Analyzer

Overview A fully automated POC Auto Dry Biochemistry Analyzer called Mispa Chem Dx, With Just 3 to 4 drops (100ul) of whole blood to test up to 19 General and Special chemistry tests in less than 12 minutes. Mispa Chem Dx works on absorption spectroscopy where a change in absorbance is detected by an absorption spectrum and an algorithm is used to calculate the end concentration of the sample in the reagent dry disc. The reagent disc consists of lyophilized reagent beads, diluent, and calibration details in the QR code. The reagent disc contains an intelligent internal quality control system IQC which continuously monitors the disc function to ensure reaction stability and optimal disc performance, IQC is the engine that drives the Mispa Chem Dx accurately and precisely Low Sample Consumption Easy to Use Maintenance Free Accurate Result Disposable reagent disc Sample volume: 100µl Testing time: 12 minutes / sample Temperature: 37°C ± 0.3°C Resolution: 0.001Abs Absorbance: 0-3.0Abs Sample type: Heparinized whole blood, serum, plasma (heparin) QC&Calibration: IQC (Intelligent Quality Control/Calibration) Work condition: Temperature:10-30°C Humidity: 30%-70% Testing method: End point, kinetic, fixed time, turbidmetry etc Light source: 12V/20W, Halogen tungsten lamp with life span over 2500 hours Power supply: AC 100V-240V, 50-60Hz Display: Android 7.0 inch 800*480, multi-point capacitive touch screen Storage: 500,000 results Printer: Built-in thermal printer Interface: 4 USB ports, 1 LAN port Dimension: 315*375*475mm. 4.2kg(N.W.), 7kg(G.W.)

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Fluorescence Immunoassay Analyzer

The FineCare FIA Meter II plus SE is a top-class fluorescence immunoassay analyzer with a built-in thermal printer, Wifi, internet connectivity, large LCD display for testing common clinical diseases. Description The FineCare FIA Meter II plus is a top-class fluorescence immunoassay analyzer with a built-in thermal printer, Wifi, and internet connectivity, large LCD display for testing common clinical diseases. Technical Specifications Analyses common clinical diseases such as Diabetic & Renal injury Markers, Thyroid function, Fertility, Cardiac Markers, Inflammation Markers, Tumour Markers Built-in Thermal Printer Real-time auto printing Support for external printer Dimension :- 239mm x 278mm x 148mm Weight : 3.3kg Large Display 8” LCD Capacitive touch screen Intuitive user interface Specially designed sampler for a small volume of the specimen. Test Reagent Suitable for whole blood, serum, plasma, and urine Room temperature storage Get results in 3 -15 minutes Test Device Tray Multiple testing modes available Unique quick mode for a large number of samples Keywords large number fluorescence small volume Cardiac Markers Thyroid function large LCD display Inflammation Markers Renal injury Markers internet connectivity common clinical diseases LCD Capacitive touch screen Intuitive user Built-in Thermal Printer Immunoassay Analyzer, Finecare Analyzer, TSH, HbA1c, Point of care , immunoassay, Clia Analyses common clinical diseases such as Diabetic & Renal injury Markers, Thyroid function, Fertility, Cardiac Markers, Inflammation Markers, Tumour Markers

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Clinical Chemistry

ADVIA 2400 Chemistry System The right balance of speed and efficiency The ADVIA® 2400 Clinical Chemistry System manages the most demanding workloads and meets high turnaround-time (TAT) goals. Its menu includes methods for testing drugs-of-abuse, therapeutic drugs (TDM) and new assays such as cystatin C and CardioPhase® hsCRP. The ADVIA 2400 Clinical Chemistry System offers: High throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage heavy workloads Rapid, consistent, 2-second cycle time for faster tube speed and test throughput User-defined automatic repeat, dilution, and reflex testing Large onboard reagent capacity and optional concentrated reagents help to minimize intervention demands Refrigerated onboard storage of controls and reagents for extended stability and increased productivity Automation-ready design: no additional hardware required Features & Benefits The ADVIA 2400 Clinical Chemistry System meets today’s high turnaround-time goals with a throughput of up to 2400 tests/hour. In addition to assays for general and specialty chemistries, its menu includes assays for specific protein measurement, drugs-of-abuse testing (DAT), and therapeutic drug monitoring (TDM). Interesting new assays such as cystatin C, HbA1c with automated sample pretreatment, and CardioPhase® hsCRP can now be included in your routine testing. The ADVIA 2400 Chemistry System pushes productivity levels while maintaining the reliability and stability that keep laboratories up and running. A rapid, 2-second probe cycle time maximizes tube speed and test throughput and combines with the system’s efficient automation-readiness to provide the turnaround time needed for high-volume laboratories Superior Speed and Productivity Throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage the heaviest workloads Rapid, consistent, 2-second cycle time Throughput of 200 tubes per hour, even when running three ISE tests and nine photometric tests per sample Automatic Sample Retain technology, auto-repeat, auto-dilution, and auto-reflex testing Automation-ready Point-in-space aspiration enables connectivity to a track. Redundant sample loading provides built-in backup and easy handling of non-routine samples. Direct sampling from track prevents tubes being detained at an analyzer and reduces aliquoting. Minimal Need for Operator Intervention Minimal-maintenance ISEs Large onboard reagent capacity and optional concentrated reagents for fewer interruptions No-maintenance, 37°C incubation oil bath Auto-calibration and auto-QC from refrigerated onboard calibrators and controls Microvolume technology with 32,000 tests onboard and up to 60 days' onboard stability for improved walkaway time. Concentrated reagents for increased maximum capacity. Remote diagnostics and Inter-Laboratory Quality Control (ILQC) options Exceptional Reliability Sample integrity check for icterus, hemolysis, and lipemia Sample probe with automatic clot/clog detection, liquid-level sensing, short-sample detection, and crash protection Advances in onboard reagent stability, calibration frequency, reduction in interferences, and expanded assay linearity

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