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Clinical Chemistry

Infinite Liquid a-Amylase 12 ml Diagnostic Reagent from Accurex (Pack Size : 6 x 2 ml). a-Amylase reagent is used for determination of amylase activity based on kinetic method using Gal G2 – a CNP. Amylase is a ready-to-use reagent. Normal amylase level is 40 to 140 units per liter (U/L) or 0.38 to 1.42 microkat/L (µkat/L). Infinite a-Amylase can be used on any Spectrophotometer, Discrete semiautomated & Automated analyzers. Reaction type is Kinetic. Accurex Biomedical is the first biochemical reagents manufacturing company in India About Infinite a-Amylase ‘is a reagent set for determination of amylase activity based on kinetic method using Gal G2 – a CNP. Infinite a-Amylase is a ready-to-use reagent. Infinite a-Amylase can be determined in just 21/2 minutes at 37°C. Infinite a-Amylase is linear upto 2000 IU/1. Infinite a-Amylase is a High Stability Reagent. Infinite a-Amylase can be used on any Spectrophotometer, Discrete semiautomated and Automated analyzers. Programme can be designed for any specific analyzer upon request. Pack Size : 6 x 2 ml Principle Amylase test involves use of a chromogenic substrate Gal G, – a CNP (2-chloro-4-nitrophenyl linked with galactosyl maltoside). The direct action of amylase with this substrate results in the release of more than 90% of 2-chloro-4-nitrophenol, which can be monitored by kinetic assay at 405 nm. The increase in absorbance is directly proportional to the amylase activity in the sample. Quality Control To ensure adequate quality control, it is recommended that each batch should include a normal and abnormal commercial reference control serum. It should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect the performance of this test include proper instrument function, temperature control, cleanliness of glassware and accuracy of pipetting. Other Details Mix thoroughly and transfer the assay mixture immediately to the thermostated cuvette and start the stopwatch simultaneously. Record the first reading at 60 second and subsequently three more readings with 30 seconds interval at 405 nm.

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Clinical Chemistry

Acid Phosphatase Diagnostic Reagent (Pack size: 8 x 1 ml) from Accurex. Acid Phosphatase is used in accordance with ISO 14189 to detect acid phosphatase from Clostridium perfringens. Autozyme Acid Phosphate reagent is set for determination of Acid Phosphatase activity based on Kinetic method using a-naphthyl phosphate. In acidic pH of the buffer system, the reagent hydrolyses a-naphthyl phosphate to a-naphthol & phosphate. Accurex has gained considerable expertise in manufacturing & marketing of In-vitro Diagnostic reagents. About Autozyme Acid Phosphate is a reagent set for determination of Acid Phosphatase activity based on Kinetic method using a-naphthyl phosphate Autozyme Acid Phosphate is a single reagent system using one step procedure Autozyme Acid Phosphate can be determined in just 8 minutes at 37 degree C Acid Phosphate can be used on any Spectrophotometer, Discrete semi automated and Automated Analyzer. Programme can be designed for any specific analyzer upon request. Pack Size : 8 x 1 ml Principle In acidic pH of the buffer system, Acid Phosphatase hydrolyses a-naphthyl phosphate to a-naphthol and phosphate. The o-naphthol is then coupled with Diazotized Fast Red TR to form a Diazo dye which has strong absorbance at 405 nm. The increase in absorbance is directly proportional to the level of acid phosphatase in serum. The addition of L-Tartrate inhibits prostatic acid phosphatase but does not inhibit other isoenzymes. The activity of Prostatic Acid Phosphatase is obtained by subtracting the result of Non prostatic Acid phosphatase (Determination with Tartrate) from Total Acid Phosphatase (without tartrate). Quality Control To ensure adequate quality control it is recommended that each batch should include a normal and an abnormal commercial reference control serum. It should be realized that the use of quality control material checks both instrument and reagent functions together. Factors which might affect ne performance of this test includes proper instrument function, temperature control, cleanliness of glassware and accuracy of pipetting.

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Hematology

VES MATIC 5 is the next-generation automated module manufactured by Diesse Diagnostica (Italy), a highly advanced, Intelligent, Intuitive & Interactive Graphic user Interface for estimating ESR using EDTA samples. Product Features: Automated instrument for the determination of ESR directly from EDTA vacutainers Faster TAT by loading 216 sample tubes at a time Pediatric samples can be processed in microtainers Reliable results with Temperature correction facility Accurate results by eliminating manual HCT correction in Anaemic samples Real-Time monitoring of samples Detection of Lipemic, Hemolyzed, Coagulated samples Standardization in mixing with Inbuilt Mixer Analyser P. Code Product Name Pack size Vesmatic 5 165941 Next 5K Transponder 1x 5000 Vesmatic 5 165942 Next 10 K Transponder 1x 10000 Display - 19" Full HD (1920x1080) LCD with PCAP Touch Screen Peripheral Control - based on Everex distributed control system with peripheral motor control boards Operating system - Linux Analysis module - 89 Positions for Sample Tubes Sample Loading - up to 18 racks simultaneously Throughput - 190 samples per hour. First result after 28 minutes Walk away mode - Supported Continuous loading - Supported Sample mixing - with multiple 180° rotations of the tubes Collection of analysed samples - reinserted into the original loading rack LIS Connection - Multiple LIS connection protocols are available: ASTM / Proprietary Remote diagnostics - available via Ethernet connection. Printer -Alphanumeric with 58mm-wide thermal paper, 36 characters per line, speed 20 mm/sec. Imaging System - 2 high resolution cameras for sample identification and analysis; 1 standard camera for internal inspection Image processor - Dedicated Quad Core CPU with integrated GPU for real-time HD image processing of samples Temperature range in operation - from +15 to + 35°C; Storage from + 5°C to + 45°C Humidity range - from 20% to 80% without condensation Central unit - Quad core ARM Cortex A-53 CPU ARM Cortex A-53, 16 GB eMMC, 4 GB RAM Interfaces - 2 x RS232C, 2 Host USB, 1 Client USB, Ethernet Protection category - CLASS I Safety standard - EN 61010-1, EN 61010-2-081, EN 61010-2-101 EMC - EN61326-1 Installation category - II Mains voltage - 230VAC@50Hz; US/Canada: 110-120Vac@60Hz Electrical energy consumption - 420VA Fuse block - 2 x 5.0 AT (delayed) (5 x 20 mm) UL Dimensions (mm) - 850 (W) x 750 (H) x 830 (D) Weight - 80 kg

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Intended Use The 4th Generation HCV TRI-DOT is a rapid, visual, sensitive and qualitative in vitro diagnostic test for the detection of (IgM,IgG & IgA) antibodies to Hepatitis C virus in human serum or plasma. It has been developed and designed with increased sensitivity for core and NS3 antibodies using a unique combination of modified HCV antigen. Salient Features Based on “Flow Through Technology”, which is similar to Elisa technology because of involvement of washing steps at various levels to enhance the specificity. Use of highly purified HCV antigens for Core, NS3, NS4, NS5 immobilized on the device. Detection of all the subtypes of HCV. Results within 3 minutes. In built quality control dot which validates the test. 100% Sensitivity & 98.9% Specificity as per WHO evaluation. Shelf life : 24 months at 2-8°C

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Rapid Test

Intended Use Diagnos Dengue card is a rapid solid phase Immuno-chromatographic test for the qualitative differential detection of IgM and IgG antibodies to dengue virus in Human serum /Plasma. This test is for in vitro diagnostic use only and is intended as an aid in for presumptive diagnosis between primary and secondary dengue infection. Salient Features Rapid, visual and qualitative Immunoassay. Differential detection of IgM & IgG Antibodies. Detection of all the 4 Dengue serotypes (DEN-1, DEN-2, DEN-3 and DEN-4). See through device for easy interpretation of results. Unique sample processing method ensures highest accuracy in results. Results with in 20 minutes. Longer shelf life : 30 months at 2-30°C. Convenient pack size : 10 tests Sensitivity-95% and Specificity- 97%. Principle

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Rapid Test

Intended Use Advantage Dengue NS1 Ag card is a rapid solid phase Immuno-chromatographic test for the qualitative detection of Dengue NS1 Antigen in Human serum /Plasma.This test is for in vitro diagnostic use only and is intended as an aid in the earlier diagnosis of Dengue Infection. Salient Features Rapid test based on lateral flow technique. Detection of Dengue in the seronegative stage i.e. from Day 1 of fever. Detection of all the 4 Dengue serotypes (DEN-1, DEN-2, DEN-3 and DEN-4). Results with in 20 minutes Longer shelf life : 30 months at 2-30°C. Convenient pack size : 25 tests Sensitivity-96% and Specificity- 98%

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Rapid Test

ntended Use The 4th Generation DIAGNOS HCV BI-DOT is a visual, rapid, sensitive and qualitative in vitro diagnostic test for the detection of (IgM,IgG & IgA) antibodies to Hepatitis C Virus in human serum or plasma. The 4th Generation DIAGNOS HCV BI-DOT has been developed and designed with increased sensitivity for core and NS3 antibodies using a unique combination of modified HCV antigens. Salient Features Rapid ,visual 4th generation test. Based on Flow Through Technology. Use of unique combination of Core, NS3, NS4, NS5 antigen. Detects all the subtypes of HCV. Result with in 3 min. Shelf life : 24 months at 2-8°C. Sensitivity- 100 %. Specificity- 99.8 %.

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Rapid Test

Intended Use The HIV TRI-DOT test is a visual, rapid, sensitive and accurate immunoassay for the differential detection of HIV-1 & HIV-2 antibodies (IgG,IgM & IgA) in human serum or plasma using HIV-1 & HIV-2 Antigens immobilized on an immunofiltration membrane. The test is a screening test for Anti HIV-1 and HIV-2 and is for in vitro diagnostic use only. Salient Features Rapid visual test ,based on Flow Through Technology. Differential detection of HIV-1 & HIV-2. Detection of group ‘O’ & subtype ‘C’. Use of envelop antigens gp41& C terminus of gp120 for HIV-1 & gp36 for HIV-2. 100% sensitivity & 100% specificity as per WHO Evaluation. Shelf life 24 months at 2-8°C Available in convenient pack sizes- 50 Tests and 100 Tests. Results within 3 minutes. No instrument required. In built quality control dot.

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Rapid Test

Intended Use The 4th Generation HIV TRI-DOT + Ag test is a visual, rapid, sensitive and accurate immunoassay for the differential detection of HIV-1 p24 antigen and HIV-1 & HIV-2 antibodies (IgM,IgG & IgA) in Human Serum or Plasma. The test is a screening test for p24 antigen (HIV-1), anti-HIV-1 & anti-HIV-2 and is for in vitro diagnostic use only. It is intended for screening of blood donors or other individuals at risk for HIV-1 & HIV-2 infection and for clinical diagnostic testing. Salient Features Rapid visual test ,based on enzyme immuno assay & Flow Through Technology. Rapid test for simultaneous and differential detection of p24 Antigen & antibodies for HIV on the same device. Ideal for Blood screening: detects sero-negative HIV Cases. Use of gp-41, C terminus of gp120 for HIV-1 antibodies & gp-36 for HIV -2 antibodies. Detection of Group ‘0’ & subtype ‘C’ of HIV-1, which is most prevalent in India. Unique washing steps for clear Interpretation of Results. Evaluated by National Institute of Biologicals- 100 % Sensitivity & 100 % Specificity. Long Shelf life: 15 months at 2-8° C.

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